CP Pharma Betamethasone Cream 0.1% ww

Country: Малезија

Језик: Енглески

Извор: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активни састојак:

Betamethasone 17 Valerate

Доступно од:

Hovid Pharmacy Sdn. Bhd.

INN (Међународно име):

Betamethasone 17 Valerate

Јединице у пакету:

15 gm

Произведен од:

HOVID BERHAD

Информативни летак

1
CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)
_ _
CP PHARMA BETAMETHASONE CREAM
0.1% W/W
Betamethasone 17 Valerate (0.1 % w/w)
WHAT IS IN THIS LEAFLET?
1.
What CP Betamethasone Cream
is used for?
2.
How CP Betamethasone Cream
works?
3.
Before you use CP
Betamethasone Cream
4.
How to use CP Betamethasone
Cream
5.
While you are using CP
Betamethasone Cream
6.
Side effects
7.
Storage and disposal of CP
Betamethasone Cream
8.
Product description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
11.
Serial number
WHAT CP BETAMETHASONE CREAM IS
USED FOR
This medicine contains the active
ingredient Betamethasone (as 17-
valerate).
CP Betamethasone Cream is a potent
topical corticosteroid indicated for
adults, elderly and children over 1
year for the relief of the inflammatory
and pruritic manifestations of steroid
responsive dermatoses (skin disease).
These include the following:

Atopic dermatitis (including
infantile atopic dermatitis) (skin
disease)

Nummular dermatitis (discoid
eczema)

Prurigo nodularis (skin disease
characterized by itchy nodules
which usually appear on the arms
or legs)

Psoriasis (excluding widespread
plaque psoriasis)
(skin disease
marked by red, itchy, scaly
patches)

Lichen simplex chronicus
(neurodermatitis) and lichen
planus (itchy patch of skin)

Seborrheic dermatitis (skin
inflammation)

Irritant or allergic
contactdermatitis

Discoid lupus erythematosus
(chronic skin condition of sores
with inflammation and scarring)

Adjunct to systemic steroid
therapy in generalized
erythroderma

Insect bite reactions

Miliara (prickly heat)
HOW CP BETAMETHASONE CREAM
WORKS
CP Betamethasone Cream contains
Betamethasone Valerate which
belongs to a group of medicines called
topical corticosteroids.
CP Betamethasone Cream works by
reducing inflammation of the skin thus
relieving the symptoms of redness,
swelling and itchiness in certain skin
conditions.
BEFORE YOU USE CP BETAMETHASONE
CREAM
_-_
_ _
_When you must not use it _
Do not take this medicin

Карактеристике производа

CP PHARMA BETAMETHASONE CREAM 0.1% W/W
DESCRIPTION
White opaque cream.
COMPOSITION
Betamethasone (as 17-valerate) 0.1% w/w
PHARMACODYNAMICS
Betamethasone valerate is topical corticosteroids which act as
anti-inflammatory agents
via multiple mechanisms to inhibit late phase allergic reactions
including decreasing the
density of mast cells, decreasing chemotaxis and activation of
eosinophils, decreasing
cytokine production by lymphocytes, monocytes, mast cells and
eosinophils, and inhibiting
the metabolism of arachidonic acid.
Topical
corticosteroids
have
anti-inflammatory,
antipruritic,
and
vasoconstrictive
properties.
PHARMACOKINETICS
Absorption
Topical corticosteroids can be systemically absorbed from intact
healthy skin. The extent of
percutaneous
absorption
of
topical
corticosteroids
is
determined
by
many
factors,
including the vehicle and the integrity of the epidermal barrier.
Occlusion, inflammation
and/or other disease processes in the skin may also increase
percutaneous absorption.
Distribution
The use of pharmacodynamics endpoints for assessing the systemic
exposure of topical
corticosteroids is necessary because circulating levels are well below
the level of detection.
Metabolism
Once
absorbed
through
the
skin,
topical
corticosteroids
are
handled
through
pharmacokinetic pathways similar to systemically administered
corticosteroids. They are
metabolised, primarily in the liver.
Elimination
Topical corticosteroids are excreted by the kidneys. In addition, some
corticosteroids and
their metabolites are also excreted in the bile.
INDICATIONS
CP Betamethasone Cream is a potent topical corticosteroid indicated
for adults, elderly
and children over 1 year for the relief of the inflammatory and
pruritic manifestations of
steroid responsive dermatoses. These include the following:
-
Atopic dermatitis (including infantile atopic dermatitis)
-
Nummular dermatitis (discoid eczema)
-
Prurigo nodularis
-
Psoriasis (excluding widespread plaque psoriasis)
-
Lichen simplex chronicus (neurodermatitis) and lichen planu