Država: Armenija
Jezik: angleščina
Source: Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում
doxazosin (doxazosin mesylate)
KRKA d.d.
doxazosin (doxazosin mesylate)
4mg
tablets
Prescription
1.3.1 Doxazosin mesylate SPC, Labeling and Package Leaflet SmPCPIL039798_3 17.05.2013 – Updated: 09.12.2013 Page 1 of 7 1. NAME OF THE MEDICINAL PRODUCT Kamiren ® 4 mg tablets 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains 4 mg doxazosin as 4.86 mg doxazosin mesylate, respectively. Excipient: tablets of 4 mg lactose 76 mg For a full list of excipients, see section 6.1. 3. PHARMACEUTICAL FORM Tablet. 4 mg tablets: white, round, flat, bevel-edged, tablets with a score on one side. 4. CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Treatment of mild and moderate hypertension (as monotherapy or in combination with other antihypertensive drugs). Relief of symptoms in benign prostatic hyperplasia. 4.2 POSOLOGY AND METHOD OF ADMINISTRATION Dosage should be adjusted according to the response and/or possible undesirable effects in individual patients. It is administrated once daily _per os_ (morning or evening) irrespective of meal time, without chewing and by washing down with enough water. If a dose is missed, it should be taken as soon as possible. However, if it is almost time for the next scheduled dose, the patient should skip the missed one and go back to the regular dosing schedule. It is important that the drug is taken regularly. If a patient does not take the drug for a few days, the new therapeutic course should be started with the lowest dose. The tablet for dosage 4 mg can be divided into equal halves. _Hypertension_ The initial dose of doxazosin is 1 mg daily. The first dose should be taken in the evening at bedtime. With regard to the effect of the drug on blood pressure, the dosage may be gradually, at 1- to 2-week intervals, titrated upwards first to 2 mg, then to 4 mg and 8 mg doxazosin once daily. Doses of 2 mg to 8 mg doxazosin a day are usually sufficient. The maximum allowed daily dose is 16 mg. _Benign prostatic hyperplasia in normotensive patients_ The initial dose of doxazosin is 1 mg daily. The first dose should be taken in the evening at bedtime. With regard to the effect Preberite celoten dokument