CLIMARA 75 PATCH

Država: Kanada

Jezik: angleščina

Source: Health Canada

Aktivna sestavina:

ESTRADIOL (ESTRADIOL HEMIHYDRATE)

Dostopno od:

BAYER INC

Koda artikla:

G03CA03

INN (mednarodno ime):

ESTRADIOL

Odmerek:

75MCG

Farmacevtska oblika:

PATCH

Sestava:

ESTRADIOL (ESTRADIOL HEMIHYDRATE) 75MCG

Pot uporabe:

TRANSDERMAL

Enote v paketu:

4

Tip zastaranja:

Prescription

Terapevtsko območje:

ESTROGENS

Povzetek izdelek:

Active ingredient group (AIG) number: 0106457036; AHFS:

Status dovoljenje:

APPROVED

Datum dovoljenje:

2007-03-08

Lastnosti izdelka

17β)
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John’s wort.
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17β. Upon application to
17β, the major estrogenic hormone secreted by the human ovary.
17β is the predominant estrogen produced by the ovaries in
premenopausal women.
17β), and provides controlled delivery of estradiol
17β,
17β), and provides controlled delivery of estradiol
17β, 0.05
17β), and provides controlled delivery of estradiol
17β,
17β)
PART II: SCIENTIFIC INFORMATION
β
2 •
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17β per day) is not approved for
completed the study. Both CLIMARA 50 and CLIMARA 100 were
significantly (p ≤ 0.05) more
efficacy parameters. Statistically significant (p ≤ 0.05) treatment
effects with both doses were
–
change from baseline significantly (p≤0.05) less for placebo group
than for the CLIMARA 50 and CLIMARA 100
Mean score significantly (p≤0.05) less for the placebo group than
for the CLIMARA 50 and CLIMARA 100
CLIMARA 50 and CLIMARA 100 statistically significant at p ≤ 0.05.
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Mean score significantly (p ≤ 0.05) less for the for the CLIMARA 50
group than for the CLIMARA 100
Mean score significantly (p ≤ 0.05) less for the for the CLIMARA 50
group than for the CLIMARA 100 group, and, mean score
significantly (p ≤ 10.05) less for the
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Patient’s Assessment
Investigator’s Assessment
Patient’s Assessment
Investigator’s Assessment
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<0.0001‡
<0.0001 ‡
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<0.0001 ‡
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‡ p < 0.05
17β per day) is not approved for sale in Canada.
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0.0141 ‡
<0.0001 ‡
0.0001 ‡
<0.0001 ‡
<0.0001 ‡
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‡ p < 0.05
17β per day) is not approved for sale in Canada.
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crease in bone mineral density at the hip (trochanteric region,
Ward’s triangle, femoral neck) and spine
Ward’s Triang