Azithromycin-GA

Država: Avstralija

Jezik: angleščina

Source: Department of Health (Therapeutic Goods Administration)

Aktivna sestavina:

Azithromycin

Dostopno od:

Medis Pharma Pty Ltd

Razred:

Medicine Registered

Lastnosti izdelka

Azithromycin-GA 500mg  PI200313A 
Azithromycin-GA 

PRODUCT INFORMATION 

NAME OF THE MEDICINE 

Azithromycin (as monohydrate).  The chemical name for
azithromycin monohydrate is 9-deoxo-9a-
aza-9a-methyl-9a-homoerythromycin A monohydrate.   

The structural formula of azithromycin monohydrate is: 

.H
2
O 

C
38
H
72
N
2
O
12
.H
2
O 
Molecular weight: 767.01 
Cas No.: 121470-24-4 

DESCRIPTION 

Azithromycin monohydrate is a white or almost-white powder.   

Azithromycin-GA tablets contain 500 mg of azithromycin (as
monohydrate).  The tablets also 
contain the following excipients: calcium hydrogen phosphate
anhydrous, pregelatinised maize 
starch,
croscarmellose sodium, sodium lauryl sulfate, magnesium stearate
and Opadry AMB 
Complete film coating system  OY-B-28920 White
(Proprietary Ingredient ID: 4271).  The tablets 
are gluten free. 

PHARMACOLOGY 

MECHANISM OF ACTION  

Azithromycin acts by binding to the 50S ribosomal subunit of
susceptible organisms, thus 
interfering with microbial protein synthesis.
Nucleic acid synthesis is not affected. 

MICROBIOLOGY 

AZITHROMYCIN DEMONSTRATES ACTIVITY _IN VITRO_ AGAINST A
WIDE RANGE OF BACTERIA INCLUDING:  

  GRAM-POSITIVE AEROBIC BACTERIA.  _Staphylococcus
aureus_, _Streptococcus pyogenes_ (group A 
beta-haemolytic Streptococci), _Streptococcus pneumoniae_,
alpha-haemolytic Streptococci 
AZITHROMYCIN-GA – Product information 
2 

Azithromycin-GA 500mg  PI200313A 
(viridans group) and other Streptococci, and _Corynebacterium
diphtheriae_.  Azithromycin 
demonstrates cross resistance with erythromycin
resistant gram-positive strains, including 
_Streptococcus faecalis _(enterococcus) and most strains
of methicillin resistant 
Staphylococci. 

  GRAM-NEGATIVE AEROBIC BACTERIA.  _Haemophilus
influenzae _(including beta-lactamase 
producing  _Haemophilus influenzae_),  _Haemophilus
parai