AMINOSYN II isoleucine lysine acetate methionine phenylalanine threonine tryptophan valine arginine aspartic acid glutamic histi

Država: Združene države Amerike

Jezik: angleščina

Source: NLM (National Library of Medicine)

Aktivna sestavina:

ISOLEUCINE (UNII: 04Y7590D77) (ISOLEUCINE - UNII:04Y7590D77)

Dostopno od:

Hospira, Inc.

INN (mednarodno ime):

ISOLEUCINE

Sestava:

ISOLEUCINE 462 mg in 100 mL

Tip zastaranja:

PRESCRIPTION DRUG

Status dovoljenje:

New Drug Application

Lastnosti izdelka

AMINOSYN II- ISOLEUCINE, LEUCINE, LYSINE ACETATE, METHIONINE,
PHENYLALANINE, THREONINE,
TRYPTOPHAN, VALINE, ALANINE, ARGININE, ASPARTIC ACID, GLUTAMIC ACID,
HISTIDINE, PROLINE, SERINE, N-
ACETYL-TYROSINE, AND GLYCINE INJECTION, SOLUTION
HOSPIRA, INC.
----------
AMINOSYN II
SULFITE-FREE
_AN AMINO ACID INJECTION_
Flexible Plastic Container
R only
DESCRIPTION
Aminosyn II, Sulfite-Free, (an amino acid injection) is a sterile,
nonpyrogenic solution for intravenous
infusion. Aminosyn II is oxygen sensitive. The following formulations
are available:
AMINOSYN II FORMULATIONS
ESSENTIAL AMINO ACIDS (MG/100 ML)
AMINOSYN II
7%
8.5%
10%
Isoleucine
462
561
660
Leucine
700
850
1000
Lysine (acetate)*
735
893
1050
Methionine
120
146
172
Phenylalanine
209
253
298
Threonine
280
340
400
Tryptophan
140
170
200
Valine
350
425
500
*Amount cited is for lysine alone and does not include the acetate.
NONESSENTIAL AMINO ACIDS (MG/100 ML)
AMINOSYN II
7%
8.5%
10%
Alanine
695
844
993
Arginine
713
865
1018
L-Aspartic Acid
490
595
700
L-Glutamic Acid
517
627
738
Histidine
210
255
300
Proline
505
614
722
Serine
371
450
530
N-AcetyI-L-Tyrosine
189
230
270
Glycine
350
425
500
PRODUCT CHARACTERISTICS
AMINOSYN II
7%
8.5%
10%
Protein Equivalent
70
85
100
®
x
®
Protein Equivalent
(approx. grams/liter)
70
85
100
Total Nitrogen
(grams/liter)
10.7
13.0
15.3
Osmolarity
(mOsmol/liter)
589
706
1040
pH
(range)
5.8
5.0—6.5
5.8
5.0—6.5
5.8
5.0—6.5
Contains sodium hydroxide for pH adjustment.
ELECTROLYTES (MEQ/LITER)
AMINOSYN II
7% 8.5% 10%
Sodium (Na )
25
32
38
Acetate(C H O )
50
61
72
Na from pH adjustor.
Includes acetate from lysine acetate.
The formulas for the individual amino acids present in Aminosyn II,
are as follows:
ESSENTIAL AMINO ACIDS
Isoleucine, USP
C H NO
Leucine, USP
C H NO
Lysine Acetate, USP C H N O • CH COOH
Methionine, USP
C H NO S
Phenylalanine, USP C H NO
Threonine, USP
C H NO
Tryptophan, USP
C
H N O
Valine, USP
C H NO
NONESSENTIAL AMINO ACIDS
Alanine, USP
C H NO
Arginine, USP
C H N O
L-Aspartic Acid
C H NO
HO CCH CH(NH )CO H
L-