Krajina: Spojené štáty
Jazyk: angličtina
Zdroj: NLM (National Library of Medicine)
tetracaine hydrochloride (UNII: 5NF5D4OPCI) (tetracaine - UNII:0619F35CGV)
Akorn
tetracaine hydrochloride
tetracaine hydrochloride 10 mg in 1 mL
SUBARACHNOID
PRESCRIPTION DRUG
Tetracaine hydrochloride is indicated for the production of spinal anesthesia for procedures requiring two to three hours. Spinal anesthesia with tetracaine hydrochloride is contraindicated in patients with known hypersensitivity to tetracaine hydrochloride or to drugs of a similar chemical configuration (ester-type local anesthetics), or aminobenzoic acid or its derivatives; and in patients for whom spinal anesthesia as a technique is contraindicated. The decision as to whether or not spinal anesthesia should be used for an individual patient should be made by the physician after weighing the advantages with the risks and possible complications. Contraindications to spinal anesthesia as a technique can be found in standard reference texts, and usually include generalized septicemia, infection at the site of injection, certain diseases of the cerebrospinal system, uncontrolled hypotension, etc.
1% isotonic isobaric solution: 2 mL Ampules, box of 25. NDC 17478-045-32 Storage: Store under refrigeration. Protect ampules from light.
unapproved drug other
TETRACAINE- TETRACAINE HCL INJECTION AKORN _Disclaimer: This drug has not been found by FDA to be safe and effective, and this_ _labeling has not been approved by FDA. For further information about unapproved_ _drugs, click here._ ---------- TETRACAINE 1% TETRACAINE HCL INJECTION, USP FOR PROLONGED SPINAL ANESTHESIA RX ONLY DESCRIPTION Tetracaine hydrochloride is 2-(Dimethylamino)ethyl p-(butylamino)benzoate monohydrochloride. It is a white crystalline, odorless powder that is readily soluble in water, physiologic saline solution, and dextrose solution. It has the following structural formula: Tetracaine hydrochloride is a local anesthetic of the ester-linkage type, related to procaine. 1% SOLUTION: A sterile, isotonic, isobaric solution. EACH ML CONTAINS: ACTIVE: 10 mg Tetracaine Hydrochloride INACTIVES: 7.5 mg Sodium Chloride, Hydrochloric Acid and/or Sodium Hydroxide may be added to adjust pH (3.2 to 6.0) and Water for Injection, USP. Nitrogen gas has been used to displace the air in the ampules. This formulation does not contain preservatives. CLINICAL PHARMACOLOGY Parenteral administration of tetracaine hydrochloride stabilizes the neuronal membrane and prevents initiation and transmission of nerve impulses thereby effecting local anesthesia. The onset of action is rapid, and the duration is prolonged (up to two or three hours or longer of surgical anesthesia). Tetracaine hydrochloride is detoxified by plasma esterases to aminobenzoic acid and diethylaminoethanol. INDICATIONS AND USAGE Tetracaine hydrochloride is indicated for the production of spinal anesthesia for procedures requiring two to three hours. CONTRAINDICATIONS Spinal anesthesia with tetracaine hydrochloride is contraindicated in patients with known hypersensitivity to tetracaine hydrochloride or to drugs of a similar chemical configuration (ester-type local anesthetics), or aminobenzoic acid or its derivatives; and in patients for whom spinal anesthesia as a technique is contraindicated. The decision as to whether or not spinal anesthesia shoul Prečítajte si celý dokument