Krajina: Indonézia
Jazyk: indonézština
Zdroj: Badan Pengawas Obat dan Makanan RI - Indonesian Food and Drug Supervisory Agency
METHISOPRINOL
DARYA-VARIA LABORATORIA TBK - Indonesia
METHISOPRINOL
500 MG
TABLET
DUS, 1 STRIP @ 8 TABLET
DARYA-VARIA LABORATORIA TBK PLANT CITEUREUP - Indonesia
2021-01-26
1 ISOPRINOSINE® METHISOPRINOL TABLET COMPOSITION Each tablet contains Methisoprinol ………………………………….500 mg PRODUCT DESCRIPTION ISOPRINOSINE® tablet appears as white-rounded tablet with imprinted ISOPRINOSINE /NP at one side and breakline at the other side, bitter taste, and odorless. Methisoprinol is a chemical complex formed from inosine and an aminoalcohol, dimethylaminoisopropanolol at a 1:3 ratio. It is a white powder, slightly bitter, water soluble, and stable in a neutral solution. This complex was discovered by Gordon, Glasky, Lynes, and Doty, American researchers. ISOPRINOSINE® increases protein and nucleoprotein synthesis; preserves the structure and function of the polyribosomes; inhibits ribonucleases; reinforces polyribosome function; interferes with the genetic transfer of the virus to the polyribosome of the host cell and in this way stops viral multiplication. From the clinical studies made by Argentine researchers emerges the non-specific antiviral action of wide spectrum (Ink, Antonini, Andres, Stefano, and others). INDICATIONS For the treatment of recurrent genitalia herpes and herpes labialis occurring within 3 months. POSOLOGY Adults: An average of 50 mg/kg BW/day. This dosage can be increased up to 100 mg/kg BW/day with maximum dose is 3–4 g/day. All use in divided doses three to four times a day, for a maximum of 10 days. CONTRAINDICATIONS Hypersensitivity to the active substance or to any of the excipients listed in the leaflet. ISOPRINOSINE® should not be given to patients with gout and high serum uric acid levels. WARNINGS AND PRECAUTIONS Since it has an evident slight cardiac effect, care should be taken when administering to cardiac patients under digitalis. ISOPRINOSINE® should not be used on microbial infection diseases since it does not have antibacterial action. DISETUJUI OLEH BPOM : 23 JUNI 2022 EREG10008712000050 2 Methisoprinol may cause a transient elevation of baseline serum and urinary uric acid, usually remaining within the normal range (using 8 Prečítajte si celý dokument