ARMOUR THYROID porcine tablet

Krajina: Spojené štáty

Jazyk: angličtina

Zdroj: NLM (National Library of Medicine)

Aktívna zložka:

THYROID, PORCINE (UNII: 6RV024OAUQ) (THYROID, PORCINE - UNII:6RV024OAUQ)

Dostupné z:

Avera McKennan Hospital

INN (Medzinárodný Name):

THYROID, PORCINE

Zloženie:

THYROID, PORCINE 30 mg

Typ predpisu:

PRESCRIPTION DRUG

Stav Autorizácia:

unapproved drug other

Súhrn charakteristických

ARMOUR THYROID- THYROID, PORCINE TABLET
AVERA MCKENNAN HOSPITAL
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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ARMOUR® THYROID (THYROID TABLETS, USP)
RX ONLY
Rev. August 2012
DESCRIPTION
Armour® Thyroid (thyroid tablets, USP)* for oral use is a natural
preparation derived from porcine
thyroid glands and has a strong, characteristic odor. (T3 liothyronine
is approximately four times as
potent as T4 levothyroxine on a microgram for microgram basis.) They
provide 38 mcg levothyroxine
(T4) and 9 mcg liothyronine (T3) per grain of thyroid. The inactive
ingredients are calcium stearate,
dextrose, microcrystalline cellulose, sodium starch glycolate and
opadry white.
CLINICAL PHARMACOLOGY
The steps in the synthesis of the thyroid hormones are controlled by
thyrotropin (Thyroid Stimulating
Hormone, TSH) secreted by the anterior pituitary. This hormone's
secretion is in turn controlled by a
feedback mechanism effected by the thyroid hormones themselves and by
thyrotropin releasing hormone
(TRH), a tripeptide of hypothalamic origin. Endogenous thyroid hormone
secretion is suppressed when
exogenous thyroid hormones are administered to euthyroid individuals
in excess of the normal gland's
secretion.
The mechanisms by which thyroid hormones exert their physiologic
action are not well understood.
These hormones enhance oxygen consumption by most tissues of the body,
increase the basal metabolic
rate, and the metabolism of carbohydrates, lipids, and proteins. Thus,
they exert a profound influence on
every organ system in the body and are of particular importance in the
development of the central
nervous system.
The normal thyroid gland contains approximately 200 mcg of
levothyroxine (T4) per gram of gland, and
15 mcg of liothyronine (T3) per gram. The ratio of these two hormones
in the circulation does not
represent the ratio in the thyroid gland, since about 80 percent of
periph