Страна: Австралия
Язык: английский
Источник: Department of Health (Therapeutic Goods Administration)
Alprazolam
Pfizer Australia Pty Ltd
Medicine Registered
XANAX ® TABLETS _Alprazolam_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Xanax. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Xanax against the benefits this medicine is expected to have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH YOUR MEDICINE. You may need to read it again. WHAT XANAX IS USED FOR Xanax is used to treat anxiety. Anxiety or tension associated with the normal stress of everyday life usually does not require treatment with medicines. Xanax is also used to treat panic attacks. Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed Xanax for another purpose. Xanax belongs to a group of medicines called benzodiazepines. They are thought to work by their action on brain chemicals. IF YOU TAKE XANAX FOR TOO LONG, IT MAY BECOME HABIT-FORMING. BENZODIAZEPINES MAY LEAD TO PHYSICAL OR PSYCHOLOGICAL DEPENDENCE. IF YOU HAVE ANY CONCERNS, YOU SHOULD DISCUSS THIS WITH YOUR DOCTOR. This medicine is available only with a doctor's prescription. BEFORE YOU TAKE XANAX _WHEN YOU MUST NOT TAKE IT_ DO NOT TAKE XANAX IF YOU HAVE AN ALLERGY TO: • any medicine containing alprazolam • any of the ingredients listed at the end of this leaflet • any other medicine in the benzodiazepine group Some of the symptoms of an allergic reaction may include: • shortness of breath • wheezing or difficulty breathing • swelling of the face, lips, tongue or other parts of the body • rash, itching or hives on the skin. DO NOT TAKE XANAX IF YOU HAVE OR HAVE HAD ANY OF THE FOLLOWING MEDICAL CONDITIONS: • myasthenia gravis which causes severe muscle weakness • severe and chronic lung disease. DO NOT TAKE THIS MEDICINE IF YOU ARE PREGNANT. It may affec Прочитать полный документ
Version:pfpxanat10913 Supersedes: pfpxanat10711 Page 1 of 13 PRODUCT INFORMATION XANAX ALPRAZOLAM NAME OF THE MEDICINE Xanax ® alprazolam 250 microgram, 500 microgram, 1 mg and 2 mg tablets DESCRIPTION Xanax tablets contain alprazolam, an anti-anxiety, benzodiazepine derivative chemically and pharmacologically related to other drugs of this class. The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo (4,3-a) (1,4) benzodiazepine. CAS No: 28981-97-7. Alprazolam is a white crystalline powder, soluble in methanol or ethanol but with no appreciable solubility in water. It has a molecular weight of 308.76 and the following structural formula: Each Xanax tablet, to be given orally, contains 0.25, 0.5, 1, or 2 mg alprazolam. PHARMACOLOGY Pharmacological properties of alprazolam in animals appear similar to those of other benzodiazepines, that is, it produces significant anxiolytic, muscle relaxant, sleep promoting and anti-convulsant effects in appropriate animal models. The exact site and mechanism of action of benzodiazepines is unknown. It is known that they act within the central nervous system as selective depressants. Clinical studies in healthy volunteers at doses up to 4 mg/day and in patients with panic disorder at doses up to 10 mg/day, produce only effects which can be considered to be extensions of its pharmacological activities. No clinically significant effects on the cardiovascular or respiratory systems were observed. Alprazolam doses up to 10 mg/day do not clinically affect laboratory parameters or vital signs. Sleep laboratory studies in man showed that Прочитать полный документ