Страна: Малайзия
Язык: английский
Источник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Paracetamol
UNIMED SDN BHD
Paracetamol
1 x 10 Tablets; 10 x 10 Tablets; 100 x 10 Tablets; 2 x 10 Tablets; 3 x 10 Tablets
KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ _ _ _ _ UNIMOL PARACETAMOL FORTE CAPLETS 650MG Paracetamol 650mg 1 WHAT IS IN THIS LEAFLET 1. What Unimol is used for 2. How Unimol works 3. Before you use Unimol 4. How to use Unimol 5. While you are using Unimol 6. Side effects 7. Storage and disposal of Unimol 8. Product description 9. Manufactured by and Product Registration Holder 10. Date of revision WHAT UNIMOL IS USED FOR For the relief of fever For the relief from mild to moderate pain including: headache, migraine, backache, musculoskeletal pain (pain in bones, muscles, tendons, ligaments or nerves), muscle pain and sudden pain due to irritated or damaged nerve, painful periods, pain of osteoarthritis, toothache, pain after dental procedures/tooth extraction, pain after vaccination and the discomfort from colds, influenza and sore throats. HOW UNIMOL WORKS Paracetamol is a centrally acting analgesic and antipyretic with minimal anti-inflammatory properties. It works by relieving pain and reducing high temperature and fever. BEFORE YOU USE UNIMOL _-When you must not use it _ It should not be used in individuals: _ _ known to be hypersensitive to paracetamol or other components of the product. which have severe and active liver impairment. taken other paracetamol containing medicines at the same time. _-Before you start to use it_ Paracetamol should be given with care to individuals with impaired kidney or liver function. Allergy alert: Paracetamol may cause severe skin reactions. Symptoms may include skin reddening, blisters or rash. It should also be given with care to individuals with alcohol dependence. _Pregnancy and lactation_ Talk to you doctor before taking this medicine if you are pregnant, might become pregnant or are breastfeeding. _-Taking other medicines _ Inform your doctor or pharmacist before taking this medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop. Some medicines and Unimol may interfere wi Прочитать полный документ
UNIMOL PARACETAMOL FORTE CAPLETS 650MG NAME AND STRENGTH OF ACTIVE SUBSTANCE: Each caplet contains: Paracetamol ............................................ 650mg Preservative Potassium Sorbate ............................ 0.10% w/w PRODUCT DESCRIPTION: Orange colour, caplet with “UNIMOL” debossed on top and “650” debossed on bottom. PHARMACODYNAMICS: Paracetamol is a centrally acting analgesic and antipyretic with minimal anti-inflammatory properties. Analgesic The mechanism of analgesic action has not been fully determined. Paracetamol may act predominantly by inhibiting prostaglandin synthesis in the central nervous system (specifically cyclooxygenase (COX)-2) and, to a lesser extent, through a peripheral action by blocking pain-impulse generation. The peripheral action may also be due to inhibition of prostaglandin synthesis or to inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation. Antipyretic Paracetamol act centrally on the hypothalamic heat-regulating center to produce peripheral vasodilatation resulting in increase blood flow through the skin, sweating and heat loss. Paracetamol reduces fever by inhibiting the formulation and release of prostaglandins in the CNS and by inhibiting endogenous pyrogens at the hypothalamic thermos regulator center. PHARMACOKINETICS: Following oral administration paracetamol is rapidly absorbed. Paracetamol absorption takes place mainly in the small intestine and therefore the rate of absorption is depending on the rate of gastric emptying. It has been shown that drugs which delay gastric emptying also delay the absorption of paracetamol whereas metoclopramide (a drug which increases the rate of gastric emptying) accelerates absorption of the analgesic through the total amount absorbed doses not increase. The presence of food in the stomach has also been reported to reduce the rate of absorption of paracetamol. Alterations in gastric pH have no appreciable effect on paracetamol absorption. Duri Прочитать полный документ