Suxamethonium chloride 100mg/2ml solution for injection ampoules

Страна: Великобритания

Язык: английский

Источник: MHRA (Medicines & Healthcare Products Regulatory Agency)

Активный ингредиент:

Suxamethonium chloride

Доступна с:

Advanz Pharma

код АТС:

M03AB01

ИНН (Международная Имя):

Suxamethonium chloride

дозировка:

50mg/1ml

Фармацевтическая форма:

Solution for injection

Администрация маршрут:

Intravenous; Intramuscular

класс:

No Controlled Drug Status

Тип рецепта:

Valid as a prescribable product

Обзор продуктов:

BNF: 15010500; GTIN: 5099602377455

тонкая брошюра

READ ALL OF THIS LEAFLET CAREFULLY BEFORE YOU ARE GIVEN THIS MEDICINE
BECAUSE IT CONTAINS
IMPORTANT INFORMATION FOR YOU.
-
Keep this leaflet. You may need to read it again.
-
If you have any further questions, ask your doctor, nurse or
pharmacist.
-
If you get any side effects, talk to your doctor, nurse or pharmacist.
This includes any
possible side effects not listed in this leaflet. See section 4.
The name of your medicine is Suxamethonium Chloride 50mg/ml Solution
for Injection. It will be
referred to as Suxamethonium Chloride for ease hereafter.
WHAT IS IN THIS LEAFLET:
1.
What SUXAMETHONIUM CHLORIDE is and what it is used for
2. What you need to know before you are given SUXAMETHONIUM CHLORIDE
3. How to take SUXAMETHONIUM CHLORIDE
4. Possible side effects
5. How to store SUXAMETHONIUM CHLORIDE
6. Contents of the pack and other information
1.
WHAT SUXAMETHONIUM CHLORIDE IS AND WHAT IT IS USED FOR
Suxamethonium Chloride belongs to a group of medicines called muscle
relaxants. Their effect
is to block the connection between the nerves and certain muscles,
which relaxes these muscles
by temporarily paralysing them. This effect helps surgeons when
performing operations.
This medicine can also be used when a patient is put on a ventilator
to control breathing. During
this
procedure,
it
is
necessary
for
the
muscles
used
for
breathing
to
be
paralysed.
Suxamethonium Chloride can also reduce the intensity of muscle
contractions associated with
drug-induced convulsions or with electroconvulsive therapy (ECT).
2. WHAT YOU NEED TO KNOW BEFORE YOU ARE GIVEN SUXAMETHONIUM CHLORIDE
DO NOT TAKE SUXAMETHONIUM CHLORIDE
• if you are allergic to Suxamethonium Chloride, any other muscle
relaxants or any of the other
ingredients of Suxamethonium Chloride (listed in section 6)
• if you or your family have reacted badly to an anaesthetic before
such as a very high body
temperature (malignant hyperthermia)
• if
you
have
a
deficiency
of
an
enzyme,
pseudocholinesterase
which
breaks
down
suxamethonium in the body
• if you have

Характеристики продукта

OBJECT 1
SUXAMETHONIUM CHLORIDE 50MG/ML SOLUTION FOR
INJECTION
Summary of Product Characteristics Updated 28-Apr-2017 | Concordia
International - formerly AMCo
1. Name of the medicinal product
Suxamethonium Chloride 50mg/ml Solution for Injection
2. Qualitative and quantitative composition
Each 2ml of solution contains 100mg of suxamethonium chloride BP
For a full list of excipients, see section 6.1
3. Pharmaceutical form
Clear, colourless, sterile solution, intended for parenteral
administration to human beings.
4. Clinical particulars
4.1 Therapeutic indications
Suxamethonium is a short acting depolarising neuromuscular blocking
agent for producing muscular
relaxation during anaesthesia. It is used in anaesthesia as a muscle
relaxant to facilitate endotracheal
intubation, mechanical ventilation and a wide range of surgical and
obstetric procedures.
It is also used to reduce the intensity of muscle contractions
associated with pharmacologically or
electrically-induced convulsions.
4.2 Posology and method of administration
Usually by bolus intravenous injection
_Adults:_ The dose is dependent on body weight, the degree of muscular
relaxation required, the route of
administration, and the response of individual patients.
To achieve endotracheal intubation, Suxamethonium is usually
administered intravenously in a dose of
1mg/kg. This dose will usually produce muscular relaxation in about 30
to 60 seconds and has a duration
of action of about 2 to 6 minutes. Larger doses will produce more
prolonged muscular relaxation, but
doubling the dose does not necessarily double the duration of
relaxation. Supplementary doses of
Suxamethonium of 50% to 100% of the initial dose administered at 5 to
10 minute intervals will maintain
muscle relaxation during short surgical procedures performed under
general anaesthesia.
For prolonged surgical procedures, Suxamethonium may be given by
intravenous infusion as a 0.1% to
0.2% solution, diluted in 5% glucose solution or sterile isotonic
saline solution, at a rate of 2.5 to 4 mg
per mi