NP THYROID 90- levothyroxine, liothyronine tablet

Страна: Соединенные Штаты

Язык: английский

Источник: NLM (National Library of Medicine)

Активный ингредиент:

LEVOTHYROXINE (UNII: Q51BO43MG4) (LEVOTHYROXINE - UNII:Q51BO43MG4), LIOTHYRONINE (UNII: 06LU7C9H1V) (LIOTHYRONINE - UNII:06LU7C9H1V)

Доступна с:

Asclemed USA, Inc.

Администрация маршрут:

ORAL

Тип рецепта:

PRESCRIPTION DRUG

Терапевтические показания :

INDICATIONS AND USAGE: NP Thyroid® tablets (thyroid tablets, USP) are indicated: 1. As replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema, and ordinary hypothyroidism in patients of any age (children, adults, the elderly), or state (including pregnancy); primary hypothyroidism resulting from functional deficiency, primary atrophy, partial or total absence of thyroid gland, or the effects of surgery, radiation, or drugs, with or without the presence of goiter; and secondary (pituitary), or tertiary (hypothalamic) hypothyroidism (See WARNINGS). 2. As pituitary TSH suppressants, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic lymphocytic thyroiditis (Hashimoto’s), multinodular goiter, and in the management of thyroid cancer. CONTRAINDICATIONS: Thyroid hormone preparations are generally

Обзор продуктов:

HOW SUPPLIED: NP Thyroid® tablets 90 mg (1 1/2 gr) (thyroid tablets, USP) are supplied as follows: Bottles of 30: NDC 76420-569-30 (repackaged from NDC 42192-331-01) Bottles of 60: NDC 76420-569-60 (repackaged from NDC 42192-331-01) Bottles of 90: NDC 76420-569-90 (repackaged from NDC 42192-331-01) Bottles of 100: NDC 76420-569-01 (relabeled from NDC 42192-331-01) NP Thyroid® tablets are tan, round tablets, debossed on one side with “AP” and a 3-digit code on the other side as follows: 90 mg (1 1/2 grain) – “331”

Статус Авторизация:

unapproved drug other

Характеристики продукта

NP THYROID 90- LEVOTHYROXINE, LIOTHYRONINE TABLET
ASCLEMED USA, INC.
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this_
_labeling has not been approved by FDA. For further information about
unapproved_
_drugs, click here._
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NP THYROID 90
NP Thyroid® (thyroid tablets, USP) for oral use is a natural
preparation derived from
porcine thyroid glands. They contain both tetraiodothyronine sodium
(T4 levothyroxine)
and triiodothyronine sodium (T3 liothyronine) providing 38 mcg
levothyroxine (T4) and 9
mcg liothyronine (T3) per grain of thyroid. The inactive ingredients
are calcium stearate,
dextrose (agglomerated) and mineral oil. Contains no ingredient made
from a gluten-
containing grain (wheat, barley, rye).
CLINICAL PHARMACOLOGY: The steps in the synthesis of the thyroid
hormones are
controlled by thyrotropin (Thyroid Stimulating Hormone, TSH) secreted
by the anterior
pituitary. This hormone’s secretion is in turn controlled by a
feedback mechanism
effected by the thyroid hormones themselves and by thyrotropin
releasing hormone
(TRH), a tripeptide of hypothalamic origin. Endogenous thyroid hormone
secretion is
suppressed when exogenous thyroid hormones are administered to
euthyroid
individuals in excess of the normal gland’s secretion. The
mechanisms by which thyroid
hormones exert their physiologic action are not well understood. These
hormones
enhance oxygen consumption by most tissues of the body, increase the
basal metabolic
rate, and the metabolism of carbohydrates, lipids, and proteins. Thus,
they exert a
profound influence on every organ system in the body and are of
particular importance
in the development of the central nervous system. The normal thyroid
gland contains
approximately 200 mcg of levothyroxine (T4) per gram of gland, and 15
mcg of
liothyronine (T3) per gram. The ratio of these two hormones in the
circulation does not
represent the ratio in the thyroid gland, since about 80 percent of
peripheral
triiodothyronine comes from monodeiodination of levo