MILLIPRED prednisolone sodium phosphate solution

Страна: Соединенные Штаты

Язык: английский

Источник: NLM (National Library of Medicine)

Активный ингредиент:

PREDNISOLONE SODIUM PHOSPHATE (UNII: IV021NXA9J) (PREDNISOLONE - UNII:9PHQ9Y1OLM)

Доступна с:

Laser Pharmaceuticals, LLC

ИНН (Международная Имя):

PREDNISOLONE SODIUM PHOSPHATE

состав:

PREDNISOLONE SODIUM PHOSPHATE 10 mg in 5 mL

Тип рецепта:

PRESCRIPTION DRUG

Статус Авторизация:

Abbreviated New Drug Application

Характеристики продукта

MILLIPRED- PREDNISOLONE SODIUM PHOSPHATE SOLUTION
LASER PHARMACEUTICALS, LLC
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MILLIPRED™
(PREDNISOLONE SODIUM PHOSPHATE ORAL SOLUTION,
10 MG PREDNISOLONE BASE PER 5 ML)
RX ONLY
DESCRIPTION
Millipred Oral Solution (10 mg Prednisolone per 5 mL) is a dye free,
pale to light yellow solution.
Each 5 mL (teaspoonful) of Millipred Oral Solution contains 13.4 mg
prednisolone sodium phosphate
(10 mg prednisolone base) in a palatable, aqueous vehicle.
Inactive Ingredients: Millipred Oral Solution (10 mg Prednisolone per
5 mL) contains the following
inactive ingredients: anti-bitter mask, corn syrup, edetate disodium,
glycerin, grape flavor,
hydroxyethylcellulose, methylparaben, potassium phosphate dibasic,
potassium phosphate monobasic,
purified water, and sodium saccharin.
Prednisolone sodium phosphate occurs as white or slightly yellow,
friable granules or powder. It is
freely soluble in water; soluble in methanol; slightly soluble in
alcohol and in chloroform; and very
slightly soluble in acetone and in dioxane.The chemical name of
prednisolone sodium phosphate is
pregna-1,4-diene-3,20-dione,11,17-dihydroxy-21- (phosphonooxy)-
disodium salt, (11β)-. The
empirical formula is C
H Na O P; the molecular weight is 484.39. Its chemical structure is:
Pharmacological Category: Glucocorticoid
CLINICAL PHARMACOLOGY
Naturally occurring glucocorticoids (hydrocortisone), which also have
salt-retaining properties, are
used as replacement therapy in adrenocortical deficiency states. Their
synthetic analogs are primarily
used for their potent anti-inflammatory effects in disorders of many
organ systems.
Prednisolone is a synthetic adrenocortical steroid drug with
predominantly glucocorticoid properties.
21
27
2
8
Some of these properties reproduce the physiological actions of
endogenous glucocorticosteroids, but
others do not necessarily reflect any of the adrenal hormones' normal
functions; they are seen only after
administration of large therapeutic doses of the drug. The
pharmacological effects of prednisolone
which are