IDAMAN METFORMIN TABLET 500MG

Страна: Малайзия

Язык: английский

Источник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активный ингредиент:

METFORMIN HYDROCHLORIDE

Доступна с:

IDAMAN PHARMA MANUFACTURING SDN BHD

ИНН (Международная Имя):

METFORMIN HYDROCHLORIDE

Штук в упаковке:

100 Tablets; 500 Tablets

Производитель:

IDAMAN PHARMA MANUFACTURING SDN BHD

тонкая брошюра

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
_ _
IDAMAN METFORMIN TABLET 500MG
_ _
Metformin Hydrochloride (500mg)
Page 1 of 3
WHAT IS IN THIS LEAFLET
1.
What Idaman Metformin Tablet is
used for
2.
How
Idaman
Metformin
Tablet
works
3.
Before you use Idaman Metformin
Tablet
4.
How to use Idaman Metformin Tablet
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Idaman
Metformin Tablet
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of Revision
WHAT IDAMAN METFORMIN TABLET IS USED
FOR
Idaman
Metformin
Tablet
contain
metformin, a medicine to treat diabetes. It
belongs to a group of medicines called
biguanides.
Idaman Metformin Tablet is used to treat
diabetes.
It
belongs
to
a
group
of
medicines called biguanides.
Idaman Metformin Tablet is used to treat
patients with type 2 diabetes (also called
‘non-insulin dependent diabetes’) when
diet and exercise alone have not been
enough
to
control
your
blood
glucose
levels. It is used particularly in overweight
patients. Adults can take this medicine on
its own or together with other medicines
to
treat
diabetes
(medicines
taken
by
mouth or insulin).
Children 10 years and over and adolescents
can take this medicine on its own or with
insulin.
HOW IDAMAN METFORMIN TABLET WORKS
Insulin
is
a
hormone produced
by
the
pancreas that makes your body take in
glucose (sugar) from the blood. Your body
uses glucose to produce energy or stores it
for future use. If you have diabetes, your
pancreas does not make enough insulin or
your body is not able to use properly the
insulin it produces. This leads to a high
level of glucose in your blood.
Idaman Metformin Tablet helps to lower
your blood glucose to as normal a level as
possible.
If you are an overweight adult, taking this
medicine over a long period of time also
helps to lower the risk of complications
associated
with
diabetes.
Idaman
Metformin Tablet is associated with either
a stable body weight or modest weight
loss.
BEFORE
YOU
USE
IDAMAN
METFORMIN
TABLET
_-When you must no

Характеристики продукта

IDAMAN PHARMA MANUFACTURING
IDAMAN METFORMIN TABLET
500MG
DESCRIPTION
A
white to off-white, round, biconvex and film-coated tablet with
breakline on one side
COMPOSITION
Each tablet contains Metformin Hydrochloride 500mg.
PHARMACODYNAMICS
Pharmacotherapeutic group: Blood glucose lowering drugs. Biguanides;
ATC code:
A10BA02
Mechanism of action
Metformin is a biguanide with antihyperglycaemic effects, lowering
both basal and
postprandial plasma glucose. It does not stimulate insulin secretion
and therefore does
not produce hypoglycaemia.
Metformin may act via 3 mechanisms:
(1) reduction
of
hepatic
glucose
production
by
inhibiting
gluconeogenesis
and
glycogenolysis.
(2) in muscle, by increasing insulin sensitivity, improving peripheral
glucose uptake
and utilization.
(3) and delay of intestinal glucose absorption.
Metformin stimulates intracellular glycogen synthesis by acting on
glycogen synthase.
Metformin
increases
the
transport
capacity
of
all
types
of
membrane
glucose
transporters (GLUTs) known to date.
Pharmacodynamic effects
Based on published clinical data, use of metformin was associated with
either a stable
body weight or modest weight loss.
In humans, independently of its action on glycaemia, metformin has
favourable effects
on
lipid
metabolism.
Metformin
reduces
total
cholesterol,
LDL
cholesterol
and
triglyceride levels at therapeutic doses.
Clinical efficacy:
The published prospective randomised study (UKPDS) has established the
long-term
benefit of intensive blood glucose control in adult patients with type
2 diabetes.
Analysis of the results for overweight patients treated with metformin
after failure of
diet alone showed a significant reduction of the absolute risk for:
• diabetes-related complication in the metformin group (29.8
events/1000 patient-years)
versus
diet
alone
(43.3
events/1000
patient-years),
and
versus
the
combined
sulfonylurea and insulin monotherapy groups (40.1 events/1000
patient-years);
• diabetes-related mortality: metformin (7.5 events/1000
patient-years), diet alone (12.7