HYDROXYZINE HYDROCHLORIDE syrup

Страна: Соединенные Штаты

Язык: английский

Источник: NLM (National Library of Medicine)

Активный ингредиент:

Hydroxyzine Hydrochloride (UNII: 76755771U3) (Hydroxyzine - UNII:30S50YM8OG)

Доступна с:

ATLANTIC BIOLOGICALS CORP.

ИНН (Международная Имя):

Hydroxyzine Hydrochloride

состав:

Hydroxyzine Hydrochloride 10 mg in 5 mL

Администрация маршрут:

ORAL

Тип рецепта:

PRESCRIPTION DRUG

Терапевтические показания :

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus. As a sedative when used as premedication and following general anesthesia, , so their use in pre-anesthetic adjunctive therapy should be modified on an individual basis. Atropine and other belladonna alkaloids are not affected by the drug. Hydroxyzine is not known to interfere with the action of digitalis in any way and it may be used concurrently with this agent. hydroxyzine may potentiate meperidine and barbiturates The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of the drug for the individual patient. Oral

Обзор продуктов:

NDC:17856-0150-1 in a CUP of 5 SYRUPS Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. PROTECT FROM FREEZING PROTECT FROM LIGHT Dispense in a tight, light-resistant container as defined in the USP, with child-resistant closure.

Статус Авторизация:

Abbreviated New Drug Application

Характеристики продукта

HYDROXYZINE HYDROCHLORIDE- HYDROXYZINE HYDROCHLORIDE SYRUP
ATLANTIC BIOLOGICALS CORP.
----------
HYDROXYZINE HYDROCHLORIDE ORAL SOLUTION, USP (SYRUP) 10 MG/5 ML
DESCRIPTION
Hydroxyzine hydrochloride is designated chemically as (±)-2-[2-[4-(
-Chloro-α-phenylbenzyl)-1-
piperazinyl]ethoxy]ethanol dihydrochloride. Its structural formula is
as follows: _p_
for Hydroxyzine Hydrochloride Oral Solution, USP (Syrup) are: alcohol
0.5%; liquid sugar;
methylparaben; peppermint oil; propylene glycol; propylparaben;
purified water and spearmint oil. citric
acid anhydrous or sodium citrate dihydrate for pH adjustment. The pH
range is between 2.0 and 4.3.
INACTIVE INGREDIENTSIT MAY ALSO CONTAIN
CLINICAL PHARMACOLOGY
Hydroxyzine hydrochloride is unrelated chemically to the
phenothiazines, reserpine, meprobamate, or
the benzodiazepines.
Hydroxyzine is not a cortical depressant, but its action may be due to
a suppression of activity in certain
key regions of the subcortical area of the central nervous system.
Primary skeletal muscle relaxation
has been demonstrated experimentally. Bronchodilator activity, and
antihistaminic and analgesic effects
have been demonstrated experimentally and confirmed clinically. An
antiemetic effect, both by the
apomorphine test and the veriloid test, has been demonstrated.
Pharmacological and clinical studies
indicate that hydroxyzine in therapeutic dosage does not increase
gastric secretion or acidity and in
most cases has mild antisecretory activity. Hydroxyzine is rapidly
absorbed from the gastrointestinal
tract and its clinical effects are usually noted within 15 to 30
minutes after oral administration.
INDICATIONS AND USAGE
For symptomatic relief of anxiety and tension associated with
psychoneurosis and as an adjunct in
organic disease states in which anxiety is manifested.
Useful in the management of pruritus due to allergic conditions such
as chronic urticaria and atopic and
contact dermatoses, and in histamine-mediated pruritus.
As a sedative when used as premedication and following general