FREAMINE III- isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, alanine, arginine, histidin

Страна: Соединенные Штаты

Язык: английский

Источник: NLM (National Library of Medicine)

Активный ингредиент:

ISOLEUCINE (UNII: 04Y7590D77) (ISOLEUCINE - UNII:04Y7590D77), LEUCINE (UNII: GMW67QNF9C) (LEUCINE - UNII:GMW67QNF9C), LYSINE ACETATE (UNII: TTL6G7LIWZ) (LYSINE - UNII:K3Z4F929H6), METHIONINE (UNII: AE28F7PNPL) (METHIONINE - UNII:AE28F7PNPL), PHENYLALANINE (UNII: 47E5O17Y3R) (PHENYLALANINE - UNII:47E5O17Y3R), THREONINE (UNII: 2ZD004190S) (THREONINE - UNII:2ZD004190S), TRYPTOPHAN (UNII: 8DUH1N11BX) (TRYPTOPHAN - UNII:8DUH1N11BX), VALINE (UNII: HG18B9YRS7) (VALINE - UNII:HG18B9YRS7), ALANINE (UNII: OF5

Доступна с:

B. Braun Medical Inc.

ИНН (Международная Имя):

ISOLEUCINE

состав:

ISOLEUCINE 0.69 g in 100 mL

Администрация маршрут:

INTRAVENOUS

Тип рецепта:

PRESCRIPTION DRUG

Терапевтические показания :

Parenteral nutrition with 10% FreAmine® III (Amino Acid Injection) is indicated to prevent nitrogen loss or treat negative nitrogen balance in adults and pediatric patients where (1) the alimentary tract, by the oral, gastrostomy, or jejunostomy route, cannot or should not be used, or adequate protein intake is not feasible by these routes; (2) gastrointestinal absorption of protein is impaired; or (3) protein requirements are substantially increased as with extensive burns. Dosage, route of administration, and concomitant infusion of nonprotein calories are dependent on various factors, such as nutritional and metabolic status of the patient, anticipated duration of parenteral nutritional support, and vein tolerance. See WARNINGS, PRECAUTIONS, Pediatric Use , and DOSAGE AND ADMINISTRATION. Central venous infusion should be considered when amino acid solutions are to be admixed with hypertonic dextrose to promote protein synthesis in hypercatabolic or severely depleted patients, or those requiring long-term

Обзор продуктов:

10% FreAmine® III is supplied sterile and nonpyrogenic in glass intravenous infusion bottles with solid stoppers. The 1000 mL containers are packed 6 per case. Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at room temperature (25°C); however, brief exposure up to 40°C does not adversely affect the product. Protect from light until use.

Статус Авторизация:

New Drug Application

тонкая брошюра

ARGININE, HISTIDINE, PROLINE, SERINE, GLYCINE, CYSTEINE, PHOSPHORIC
ACID, AND SODIUM BISULFITE INJECTION,
SOLUTION
B. Braun Medical Inc.
----------
DIRECTIONS FOR USE OF B. BRAUN GLASS
CONTAINERS WITH SOLID STOPPERS
Designed for use with a vented set. Use 18 to 22 gauge needle size for
admixing or withdrawing solutions
from the glass bottle.
Before use, perform the following checks:
1.
Inspect each container. Read the label. Ensure solution is the one
ordered and is within the
expiration date.
2.
Invert container and carefully inspect the solution in good light for
cloudiness, haze, or particulate
matter; check the bottle for cracks or other damage. In checking for
cracks, do not be confused by
normal surface marks and seams on the bottom and sides of the bottle.
These are not flaws. Look
for bright reflections that have depth and penetrate into the wall of
the bottle. Reject any such
bottle.
3.
Remove plastic cap (see Figure 1).
4.
Swab exposed stopper surface with a suitable disinfectant.
Warning: Some additives may be incompatible. Consult with pharmacist.
When introducing
additives, use aseptic techniques. Mix thoroughly. Do not store.
5.
When adding medication to the container prior to administration, swab
the target area of the
rubber stopper, inject medication and mix thoroughly by gentle
agitation.
6.
Refer to Directions for Use of the set being used. Insert the set
spike into the bottle through the
target area of the rubber stopper. Allow the fluid to flow and remove
air from the tubing before
administration begins. Hang the container.
7.
After admixture and during administration, re-inspect the solution
frequently. If any evidence of
solution contamination or instability is found or if the patient
exhibits any signs of fever, chills or
other reactions not readily explainable, discontinue administration
immediately and notify the
physician.
8.
Spiking, additions, or transfers should be made immediately after
swabbing stopper surface.
Check for vacuum at first puncture of stopper. Admixture by needle or
s

Характеристики продукта

FREAMINE III- ISOLEUCINE, LEUCINE, LYSINE, METHIONINE, PHENYLALANINE,
THREONINE, TRYPTOPHAN,
VALINE, ALANINE, ARGININE, HISTIDINE, PROLINE, SERINE, GLYCINE,
CYSTEINE, PHOSPHORIC ACID, AND SODIUM
BISULFITE INJECTION, SOLUTION
B. BRAUN MEDICAL INC.
----------
10% FREAMINE III
(AMINO ACID INJECTION)
PROTECT FROM LIGHT UNTIL USE.
DESCRIPTION
10% FreAmine® III (Amino Acid Injection) is a sterile, nonpyrogenic,
hypertonic solution containing
crystalline amino acids. Each 1000 mL provides a total of 15.3 g of
nitrogen in 97 g of amino acids
equal to 95.6 grams of protein equivalent. All amino acids designated
USP are the "L"-isomer, with the
exception of Glycine USP, which does not have an isomer.
Each 100 mL contains:
_ESSENTIAL AMINO ACIDS_
Isoleucine USP
............................................................ 0.69 g
Leucine USP
............................................................... 0.91 g
Lysine USP
................................................................. 0.73
g
(added as Lysine Acetate USP .................................. 1.02
g)
Methionine USP
.......................................................... 0.53 g
Phenylalanine USP
....................................................... 0.56 g
Threonine USP
............................................................ 0.40 g
Tryptophan USP
......................................................... 0.15 g
Valine USP
................................................................. 0.66
g
_NONESSENTIAL AMINO ACIDS_
Alanine USP
............................................................... 0.71 g
Arginine USP
.............................................................. 0.95 g
Histidine USP
............................................................. 0.28 g
Proline USP
............................................................... 1.12 g
Serine USP
................................................................. 0.59
g
Glycine USP
............................................................... 1.40 g
Cysteine
....................................