Страна: Малайзия
Язык: английский
Источник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CYANOCOBALAMIN; FERRIC AMMONIUM CITRATE; NICOTINAMIDE/VITAMIN B3; Cobalt Gluconate
Gladron Chemicals Sdn Bhd
CYANOCOBALAMIN; FERRIC AMMONIUM CITRATE; NICOTINAMIDE/VITAMIN B3; Cobalt Gluconate
100.00 mcg/mL
Vetoquinol
_VÉTOQUINOL - MALAISIE_ _DIMENSIONS : 160 x 120 mm_ _RÉFÉRENCE ARTICLE : 412836 0214 E_ _NOM DU PRODUIT : Fercobsang 100 ml _ _(not)_ _1 COULEUR_ _281 U_ _CRÉÉ PAR : Pat. Mougenot_ _LE : 29/09/2014_ _VISA :_ _REV E_ RECONSTITUENT COMPOSITION Iron (as ammonium citrate) . . . . . . . . . . . . . . . . . . . . . . . 1.7500 mg Cyanocobalamine (vitamin B12) . . . . . . . . . . . . . . . . . . . 0.0250 mg Nicotinamide (vitamin PP) . . . . . . . . . . . . . . . . . . . . . . . 20.0000 mg Cobalt (as digluconate) . . . . . . . . . . . . . . . . . . . . . . . . . . 0.0065 mg Benzyl alcohol (E1519). . . . . . . . . . . . . . . . . . . . . . . . . . 20.8000 mg Excipient Q.S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 ml 100 ML VIAL OF ORANGE TO BROWN SOLUTION INTRAMUSCULAR (I.M.), SUBCUTANEOUS (S.C.) AND ORAL ROUTE PHARMACODYNAMICS Iron, provided by the ferric ammonium citrate, plays an essential role in oxygen metabolism and in energy metabolism. Cyanocobalamin (or vitamin B12) is a water soluble vitamin which plays a role in folate metabolism. Nicotinamide (or vitamin PP) is also a water soluble vitamin. This is an active moiety of two co-enzymes which, in association with the apoenzymes, are involved in different stages of the degradation or synthesis of carbohydrates, fatty acids and amino acids. This molecule also plays a key role during terminal oxidative degradation of substrates in the citric acid cycle by fixing hydrogen during the terminal phase and by transporting it to the flavinic enzymes of the respiratory chain. Cobalt is a trace element required for the activity of microflora in the Magny-Vernois 70200 LURE (France) rumen. In ruminants, cobalt is converted into vitamin B12 which, after absorption, participates in metabolism of propionic acid, the main energy source in these animals. PHARMACOKINETICS Iron, provided by ferric ammonium citrate, is absorbed into the duodenum and stored in the intestinal mucosa in the form of ferritin. The liver, spleen, bone marrow and muscl Прочитать полный документ