Страна: Малайзия
Язык: английский
Источник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Chondroitin Sulphate; Glucosamine Sulfate NaCl, Crystalline
AV MANUFACTURING SDN.BHD
Chondroitin Sulphate; Glucosamine Sulfate NaCl, Crystalline
14 Sachets; 3 Sachets
AV MANUFACTURING SDN.BHD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ CONART ® CAPSULE Glucosamine Sulphate/ Chondroitin Sulphate (250mg/ 200mg) CONART ® SACHET FOR ORAL SOLUTION Glucosamine Sulphate/ Chondroitin Sulphate (1500mg/ 1200mg) 1 WHAT IS IN THIS LEAFLET 1. What Conart is used for 2. How Conart works? 3. Before you take Conart 4. How to use Conart 5. While you are using Conart 6. Side effects 7. Storage and disposal 8. Product description 9. Manufacturer & product registration holder 10. Date of revision 1. WHAT CONART IS USED FOR Conart is used to relieve joint problems related to osteoarthritis. 2. HOW CONART WORKS Conart contains glucosamine which forms a key part of cartilage (the cushioning substance between bones in the joints) while chondroitin acts by preventing damage or breakdown of cartilage. Glucosamine and chondrotin act to increase synovial fluid production, thereby providing lubricant activity for proper joint function. 3. BEFORE YOU USE CONART _-When you must not use it_ If you are allergic to glucosamine or chondroitin or any of the ingredients in the product. If you are allergic to seafood. Avoid use during the first 3 months of pregnancy. _-Before you start to use it_ Read the instruction and this leaflet carefully to understand how this medication should be taken. Avoid use in children. Tell your doctor or a pharmacist if you have any medical conditions, especially any of the following: if you are pregnant, planning to become pregnant, or breastfeeding. if you have allergies to seafood, medicines or other substances. This product contains glucosamine sulphate, a seafood- derived material. It is not recommended for people with seafood allergies. if you have high blood glucose if you have severe liver and /or kidney problems _-Taking other medicines_ Talk to your doctor or a pharmacist if you are taking: any medicine for diabetes (to control the blood sugar), such as metformin, acarbose, repaglinide. Warfarin (a blood-thinning drug). Glucosamine may increase the risk Прочитать полный документ
CONART CAPSULE CONART SACHET FOR ORAL SOLUTION NAME AND STRENGTH OF ACTIVE SUBSTANCES CONART CAPSULE : Glucosamine sulphate sodium chloride 314mg equivalent 250mg glucosamine sulphate (derived from seafood) and chondroitin sulphate 200mg CONART SACHET : Glucosamine sulphate sodium chloride 1884mg equivalent 1500mg glucosamine sulphate (derived from seafood) and chondroitin sulphate 95% purity 1265mg equivalent chondroitin sulphate 1200mg PRODUCT DESCRIPTION CONART CAPSULE : Hard gelatin bovine capsule, snap-fit dark maroon/white opaque capsule with embossed “Conart” at both side. CONART SACHET : Aluminium/PE sachet containing white to off-white powder PHARMACODYNAMICS Glucosamine is a natural substance found in chitin, mucoproteins, and mucopolysaccharides. It is involved in the manufacture of glycosaminoglycan, which forms cartilage tissue in the body; glucosamine is also present in tendons and ligaments. Glucosamine must be synthesised by the body but the ability to do this declines with age. Glucosamine and its salts have therefore been advocated in the treatment of rheumatic disorders including osteoarthritis. Glucosamine also acts to improve the viscosity of synovial fluid by increasing synovial fluid production, thereby providing lubricant activity. The primary mechanism of action of CS is increased joint glycosaminoglycan concentration and a subsequent enhancement of synovial fluid viscosity. Improvement in joint structure and function are due to: (1) increased endogenous synthesis of hyaluronic acid and sulfated glycosaminoglycans from chondroitin sulfates; and (2) reduced breakdown of joint glycosaminoglycans subsequent to decreased collagenolytic activity and inhibition of enzymes, such as phospholipase A2 and N- acetylglucosaminidase, which are capable of degrading existing joint glycosaminoglycans. Glucosamine and chondroitin work synergistically to stimulate the anabolic metabolism of osteo- cartilagineous tissues by stimulating the biosynthesis of the mucopolysaccharides (which are the essential Прочитать полный документ