Страна: Малайзия
Язык: английский
Источник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Paracetamol
UNAM PHARMACEUTICAL (M) SDN BHD
Paracetamol
20tablet Tablets; 500tablet Tablets
PT MEDIFARMA LABORATORIES, INC
BIOGESIC TABLET Paracetamol 500mg _ _ _Patient Information Leaflet_ _____________________________________________________________________________________ WHAT IS IN THE LEAFLET? 1. What Biogesic tablet is used for 2. How Biogesic tablet works 3. Before you use Biogesic tablet 4. How to use Biogesic tablet 5. While you are using Biogesic tablet 6. Side effects 7. Storage and disposal of Biogesic tablet 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision 1. WHAT BIOGESIC TABLET IS USED FOR : For the relief of fever, headache and muscular pain. 2. HOW BIOGESIC TABLET WORKS The tablet 500mg Paracetamol. Paracetamol works by relieving pain. Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason. 3. BEFORE YOU USE BIOGESIC TABLET _- When you must not use it _ Do not take this medicine if you have an allergy to: - Paracetamol or any of the other ingredients listed at the end of this leaflet - any other similar medicines Do not take Biogesic tablet if you: - are taking any other paracetamol-containing products If any of these apply to you, get advice from a doctor or pharmacist. Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal. If you are not sure whether you should start taking this medicine, talk to your doctor Use in pregnancy and breastfeeding: Safe to use in normal therapeutic dose as an analgesic. Considered to be the analgesic of choice in pregnant patients. Excreted in breast milk. Maternal ingestion of paracetamol in normal therapeutic doses does not appear to present a risk to the nursing infant. _- Before you start to use it _ Tell your doctor if you have: - allergies to any other medicines, foods, preservatives or dyes. - impaired kidney or liver function. - alcohol dependency Ask your doctor or pharmacist for advice before takin Прочитать полный документ
98 mm 140 mm July 18 2011 P30000007356 Paracetamol 321210000XX 679360B-1-DW/48.13 Biogesic Tablet - ULI (Hongkong) 140 x 98 mm 1 Jorist Gatus Blue - P660C Paracetamol 500mg PRODUCT DESCRIPTION Plain tablet, orange, round 1/2" in diameter, flat face, beveled-edge, bisected, debossed with "BIOGESIC 500" logo on one side and plain on the other side. PHARMACODYNAMICS Paracetamol is a centrally acting analgesic and antipyretic with minimal anti-inflammatory properties. ANALGESIC The mechanism of analgesic action has not been fully determined. Paracetamol may act predominantly by inhibiting prostaglandin synthesis in the central nervous system (specifically cyclooxygenase (COX)-2) and, to a lesser extent, through a peripheral action by blocking pain-impulse generation. The peripheral action may also be due to inhibition of prostaglandin synthesis or to inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation ANTIPYRETIC Paracetamol act centrally on the hypothalamic heat-regulating center to produce peripheral vasodilatation resulting in increase blood flow through the skin, sweating and heat loss. Paracetamol reduces fever by inhibiting the formulation and release of prostaglandins in the CNS and by inhibiting endogenous pyrogens at the hypothalamic thermoregulator center PHARMACOKINETICS Following oral administration paracetamol is rapidly absorbed. Paracetamol absorption takes place mainly in the small intestine and therefore the rate of absorption is depending on the rate of gastric emptying. It has been shown that drugs which delay gastric emptying also delay the absorption of paracetamol whereas metoclopramide (a drug which increases the rate of gastric emptying) accelerates absorption of the analgesic through the total amount absorbed doses not increase. The presence of food in the stomach has also been reported to reduce the rate of absorption of paracetamol. Alterations in gastric pH have no appreciable effect on paracetamol absorption. Durin Прочитать полный документ