Țară: Australia
Limbă: engleză
Sursă: Department of Health (Therapeutic Goods Administration)
salbutamol sulfate, Quantity: 0.48 mg/mL (Equivalent: salbutamol, Qty 0.4 mg/mL)
GlaxoSmithKline Australia Pty Ltd
Oral Liquid
Excipient Ingredients: sodium benzoate; hypromellose; citric acid monohydrate; sodium chloride; purified water; sodium citrate dihydrate; saccharin sodium; Flavour
Oral
150mL
(S4) Prescription Only Medicine
INDICATIONS AS AT 14 FEBRUARY 2005: Ventolin is indicated for the prevention and relief of bronchospasm in bronchial asthma of all types and for the alleviation of any reversible airways obstruction associated with conditions such as chronic bronchitis or emphysema.
Visual Identification: SLIGHTLY HAZY VISCOUS LIQUID; Container Type: Bottle; Container Life Time: 3 Years; Container Temperature: Store below 30 degrees Celsius
Licence status A
2003-01-28
VENTOLIN ® SUGAR FREE SYRUP _Salbutamol sulphate_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET? Please read this leaflet carefully before you take Ventolin Sugar Free Syrup. This leaflet answers some common questions about Ventolin Sugar Free Syrup. It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Sometimes new risks are found even when a medicine has been used for many years. Your doctor has weighed the expected benefits of you taking Ventolin Sugar Free Syrup against the risks this medicine could have for you. IF THERE IS ANYTHING YOU DO NOT UNDERSTAND OR IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. IF YOU WANT MORE INFORMATION, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT IS VENTOLIN SUGAR FREE SYRUP USED FOR? Ventolin Sugar Free Syrup helps you breathe more easily. Ventolin Sugar Free Syrup works by opening up the airways tubes in your lungs when your chest is tight or when you are wheezing. Ventolin Sugar Free Syrup belongs to a group of medicines called bronchodilators. Because the medicine in your syrup gives relief from your chest symptoms, it is often called a 'reliever'. There are other types of medicines that prevent wheezing or chest tightness. These medicines are called 'preventers' and must be used every day. Your doctor may tell you to use a 'preventer' in addition to your Ventolin Sugar Free Syrup. Ventolin Sugar Free Syrup is not the only form of Ventolin available. Your doctor will decide which form of Ventolin is right for you. Your doctor may have prescribed Ventolin Sugar Free Syrup for another reason. Ventolin Sugar Free Syrup is not addictive. BEFORE YOU TAKE VENTOLIN SUGAR FREE SYRUP _DO NOT TAKE IF:_ You must not take Ventolin Sugar Free Syrup: • if you have ever had an allergic reaction to salbutamol sulphate or any of the ingredients listed toward the end of this leafl Citiți documentul complet
1 PRODUCT INFORMATION VENTOLIN SUGAR FREE SYRUP AND INJECTION NAME OF THE MEDICINE: Salbutamol Sulphate BP CHEMICAL NAME 1-(4-hydroxy-3-hydroxymethylphenyl)-2-(t-butylamino)ethanol Sulphate. STRUCTURE MOLECULAR FORMULA: (C 13 H 21 NO 3 ) 2 H 2 SO 4 DESCRIPTION: Salbutamol sulphate is a white or almost white odourless powder. It is soluble in 4 parts of water; slightly soluble in 95% alcohol, chloroform and solvent ether. Ventolin Sugar Free Syrup contains the following excipients: sodium citrate, citric acid monohydrate, hypromellose, sodium benzoate, saccharin sodium, sodium chloride, water – purified and orange flavouring. Ventolin Injection contains the following excipients: sodium chloride, sulfuric acid and water for injections. PHARMACOLOGY: Salbutamol is a relatively selective beta-2 adrenoreceptor stimulant. It is more specific than both isoprenaline and orciprenaline for adrenergic beta-2 receptors. After oral and parenteral administration, stimulation of the beta receptors in the body, both beta-1 and beta-2, occurs because (a) beta-2 selectivity is not absolute, and (b) higher concentrations of salbutamol occur in the regions of these receptors with these modes of administration. This results in the beta-1 effect of cardiac stimulation, though not so much as with isoprenaline, and beta-2 effects of peripheral vasodilatation and hypotension, skeletal muscle tremor and uterine muscle relaxation. Metabolic effects such as hyperinsulinaemia and hyperglycaemia also may occur, although it is not known whether these effects are mediated by beta-1 or beta-2 receptors. The serum potassium levels have a tendency to fall. CHOH.CH 2 .NHC(CH 3 ) 3 HOH 2 C HO H 2 SO 4 2 2 PHARMACOKINETICS Peak plasma levels occur at 2 to 4 hours after oral administration of salbutamol. The elimination half-life of oral or inhaled salbutamol is between 2.7 and 5 hours. Salbutamol is not metabolized in the lung but is converted to the 4'-o-sulphate ester in the liver. Salbutamol is excreted in the urine as free drug and as the metab Citiți documentul complet