TEPMETKO Tablets 250mg (テプミトコ錠250mg)

Țară: Japonia

Limbă: engleză

Sursă: すりの適正使用協議会 RAD-AR Council, Japan

Ingredient activ:

Tepotinib hydrochloride hydrate

Disponibil de la:

Merck Biopharma Co., Ltd

INN (nume internaţional):

Tepotinib hydrochloride hydrate

Forma farmaceutică:

whitish soft red tablet, major axis: 18 mm, minor axis: 9 mm, thickness: 6.9 mm

Rezumat produs:

Print on wrapping: テプミトコ250, Merck, TEPMETKO 250mg

Prospect

Drug Information Sheet("Kusuri-no-Shiori")
Internal
Revised: 05/2021
The information on this sheet is based on approvals granted by the
Japanese regulatory authority. Approval
details may vary by country. Medicines have adverse reactions (risks)
as well as efficacies (benefits). It is
important to minimize adverse reactions and maximize efficacy. To
obtain a better therapeutic response,
patients should understand their medication and cooperate with the
treatment.
BRAND NAME:
TEPMETKO TABLETS 250MG
ACTIVE INGREDIENT:
Tepotinib hydrochloride hydrate
DOSAGE FORM:
whitish soft red tablet, major axis: 18 mm, minor axis: 9
mm, thickness: 6.9 mm
IMPRINT OR PRINT ON WRAPPING:
テプミトコ 250, Merck, TEPMETKO 250mg
EFFECTS OF THIS MEDICINE
This medicine inhibits phosphorylation of mesenchymal epithelial
transformation (MET), that is
a receptor tyrosine kinase, and thereby inhibits downstream signaling
to suppress tumor
growth.
It is usually used to treat unresectable, advanced/recurrent non-small
cell lung cancer with
MET exon 14 skipping alterations.
THE FOLLOWING PATIENTS MAY NEED TO BE CAREFUL WHEN USING THIS
MEDICINE.BE SURE TO TELL YOUR DOCTOR
AND PHARMACIST.
・If you have previously experienced any allergic reactions (itch,
rash, etc.) to any medicines
or foods.
If you have: interstitial lung disease or its history, liver
dysfunction, or renal dysfunction.
・If you are pregnant or breastfeeding.
・If you are taking any other medicinal products. (Some medicines may
interact to enhance or
diminish medicinal effects. Beware of over-the-counter medicines and
dietary supplements
as well as other prescription medicines.)
DOSING SCHEDULE (HOW TO TAKE THIS MEDICINE)
・
Your dosing schedule prescribed by your doctor is((         

to be written by a healthcare
professional
))
・In general, for adults, take 2 tablets (500 mg of the active
ingredient) at a time, once a day
after a meal, however, the dosage will be decreased according to the
symptoms. The
dosage may be decreased to 1 ta