Nortriptyline 25mg tablets

Țară: Regatul Unit

Limbă: engleză

Sursă: MHRA (Medicines & Healthcare Products Regulatory Agency)

Ingredient activ:

Nortriptyline hydrochloride

Disponibil de la:

Medreich Plc

Codul ATC:

N06AA10

INN (nume internaţional):

Nortriptyline hydrochloride

Dozare:

25mg

Forma farmaceutică:

Oral tablet

Calea de administrare:

Oral

Clasă:

No Controlled Drug Status

Tip de prescriptie medicala:

Valid as a prescribable product

Rezumat produs:

BNF: 04030100; GTIN: 05060292741246

Prospect

6-7
20-25
44-55
10
8-11
25-35
55-77
10-20
Over 11
35-54
77-119
25-35
AGE (YEARS)
WEIGHT
DOSE (MG)
KG
LB
years
with
psychiatric
conditions
who
were
treated
with
an
antidepressant.
If you have thoughts of harming or killing yourself at any time,
contact your doctor or go to hospital straight away.
You may find it helpful to tell a relative or close friend that you
are
depressed or have an anxiety disorder, and ask them to read this
leaflet. You might ask them to tell you if they think your depression
or anxiety is getting worse, or if they are worried about changes in
your behaviour.
If any of these points apply to you, tell your doctor or pharmacist.
TAKING OTHER MEDICINES
You should tell your doctor if you are taking or have taken any
medicines, including medicines obtained without a prescription.
The following medicines may interact with your Nortriptyline Tablets:
•
guanethidine, debrisoquine, bethanidine, clonidine (used to treat
high blood pressure);
•
barbiturates (used for anxiety or to make you feel sleepy);
•
alcohol (you should not drink alcohol);
•
fluoxetine (another antidepressant);
•
cimetidine (for heartburn and ulcers);
•
phenothiazines (for mental illness);
•
carbamazepine (for epilepsy);
•
propafenone, flecainide, encainide, quinidine (for heartbeat
disorders).
•
Valproic acid (medicine used for the treatment of epilepsy and
bipolar disorder)
It may still be all right for you to be given Nortriptyline Tablets.
Your doctor will be able to decide what is suitable for you.
DRIVING AND USING MACHINES
Nortriptyline
Tablets
may
affect
alertness.
Use
caution
when
driving or operating heavy machinery until you’re aware of how
this drug affects you. If you feel Nortriptyline Tablets affect your
ability to drive or use machines, tell your doctor immediately.
IMPORTANT
INFORMATION
ABOUT
SOME
OF
THE
INGREDIENTS
OF
NORTRIPTYLINE TABLETS
Nortriptyline Tablets contain lactose. If you are lactose intolerant,
contact your doctor before taking this medicine. Nortriptyline 25 mg
Tablets contain

Caracteristicilor produsului

SUMMARY OF PRODUCT CHARACTERISTICS
1
NAME OF THE MEDICINAL PRODUCT
Nortriptyline 25mg Tablets
2
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each tablet contains nortriptyline hydrochloride equivalent to
nortriptyline 25mg
Excipient with known effect
The tablet also contains lactose monohydrate.
For full list of excipients, see section 6.1
3
PHARMACEUTICAL FORM
Tablet
White to off-white round biconvex tablets, debossed ‘NO’ on one
side and
‘25’ on the other side.
4
CLINICAL PARTICULARS
4.1
THERAPEUTIC INDICATIONS
Nortriptyline is indicated for the treatment of Major Depressive
Episodes.
4.2
POSOLOGY AND METHOD OF ADMINISTRATION
Posology
ADULTS: The usual adult dose is 25mg three or four times daily. Dosage
should begin
at a low level (50mg once daily or 25mg 2-3 times daily). If
necessary, dose could be
gradually increased in 25mg increments no more rapidly than every
other day to be
added to the morning dose. When doses above 100mg daily are
administered,
monitoring of plasma levels of nortriptyline should be considered and
maintained in
the optimum range of 50 to 150ng/ml. Doses above 150mg per day are not
recommended.
Lower than usual dosages are recommended for elderly patients. Lower
dosages are
also recommended for outpatients than for hospitalised patients who
will be under
close supervision. The physician should initiate dosage at a low level
and increase it
gradually, noting carefully the clinical response and any evidence of
intolerance.
Following remission, maintenance medication may be required for a
longer period of
time. The maintenance dose should be the same as the optimal
therapeutic dose.
If a patient develops minor side-effects, the dosage should be
reduced. The drug
should be discontinued promptly if adverse effects of a serious nature
or allergic
manifestations occur.
ELDERLY: 30 to 50mg/day in divided doses. Dosage should begin at a low
level (10 –
20 mg daily) and be increased as required to the maximum dose of 50mg.
If it is
considered necessary to use higher dosing in an elderly pat