Moduretic

Țară: Noua Zeelandă

Limbă: engleză

Sursă: Medsafe (Medicines Safety Authority)

Ingredient activ:

Amiloride hydrochloride dihydrate 5mg;  ; Hydrochlorothiazide 50mg

Disponibil de la:

Pharmacy Retailing (NZ) Ltd t/a Healthcare Logistics

INN (nume internaţional):

Amiloride hydrochloride dihydrate 5 mg

Dozare:

50mg/5mg

Forma farmaceutică:

Tablet

Compoziție:

Active: Amiloride hydrochloride dihydrate 5mg   Hydrochlorothiazide 50mg Excipient: Calcium hydrogen phosphate Guar gum Lactose Magnesium stearate Maize starch Pregelatinised maize starch Sunset yellow FCF

Unități în pachet:

Blister pack, PVC/PVdC/Al, 50 tablets

Clasă:

Prescription

Tip de prescriptie medicala:

Prescription

Produs de:

Bioindustria Laboratorio Medicinali SpA

Indicații terapeutice:

MODURETIC is indicated in the treatment of patients with: - oedema of cardiac origin; - hepatic cirrhosis with ascites; - hypertension in whom potassium depletion might be anticipated. MODURETIC, with its combination of amiloride HCl and hydrochlorothiazide, minimises the possibility of the development of excessive potassium loss in patients during vigorous diuresis for prolonged periods. MODURETIC, with its built-in potassium sparing agent, is especially indicated in those conditions where the positive effect on potassium balance is particularly important. MODURETIC may be used alone, or as an adjunct to other antihypertensive drugs. Since it enhances the action of these agents, the dosage of these antihypertensive drugs may need to be reduced to avoid the risk of an excessive drop in blood pressure.

Rezumat produs:

Package - Contents - Shelf Life: Blister pack, PVC/PVdC/Al - 50 tablets - 24 months from date of manufacture stored at or below 30°C

Data de autorizare:

2010-06-28

Prospect

MODURETIC
®

1 
MODURETIC
®

_amiloride hydrochloride 5 mg/hydrochlorothiazide 50 mg _
CONSUMER MEDICINE INFORMATION (CMI) 

WHAT IS IN THIS LEAFLET 
This leaflet answers some common 
questions about MODURETIC.  It 
does not contain all the available 
information. 
It does not take the place of talking to 
your doctor or pharmacist. 
All medicines have risks and 
benefits.  Your doctor has weighed 
the risks of you taking 
MODURETIC against the benefits 
they expect it will have for you. 
IF YOU HAVE ANY CONCERNS ABOUT 
TAKING THIS MEDICINE, ASK YOUR 
DOCTOR OR PHARMACIST. 
KEEP THIS LEAFLET WITH THE MEDICINE. 
You may need to read it again. 
WHAT MODURETIC IS 
USED FOR 
MODURETIC contains a 
combination of two diuretics, 
amiloride hydrochloride and 
hydrochlorothiazide as the active 
ingredients. 
MODURETIC is used to help reduce 
the amount of excess fluid in the 
body for people who have: 

  oedema, swelling of the ankles, 
feet and legs 

  ascites due to liver disease 
resulting in fluid accumulation in 
the stomach area. 
MODURETIC is also used to help 
people with hypertension or high 
blood pressure. 
Everyone has blood pressure.  This 
pressure helps get your blood all 
around your body.  Your blood 
pressure may be different at different 
times of the day, depending on how 
busy or worried you are.  You have 
hypertension or high blood pressure 
when your blood pressure stays 
higher than is needed, even when you 
are calm and relaxed. 
There are usually no symptoms of 
hypertension.  The only way of 
knowing that you have hypertension 
is to have your blood pressure 
checked on a regular basis.  If high 
blood pressure is not treated it can 
lead to serious health problems.  You 
may feel fine and have no symptoms, 
but even

Caracteristicilor produsului

MODURETIC – Data Sheet
Page 1 of 16
NEW ZEALAND DATA SHEET
1. PRODUCT NAME
MODURETIC 50mg/5mg Tablet
2. QUALITATIVE AND QUANTITATIVE COMPOSITION
Each tablet contains hydrochlorothiazide 50 mg and amiloride
hydrochloride
dihydrate 5 mg. For full lists of excipients, see section6.1.
3. PHARMACEUTICAL FORM
MODURETIC tablets are plain, peach, diamond shaped, compressed tablets
4. CLINICAL PARTICULARS
4.1 THERAPEUTIC INDICATIONS
MODURETIC is indicated in the treatment of patients with:
- oedema of cardiac origin;
- hepatic cirrhosis with ascites;
- hypertension in whom potassium depletion might be anticipated.
MODURETIC, with its combination of amiloride HCl and
hydrochlorothiazide,
minimises the possibility of the development of excessive potassium
loss in
patients during vigorous diuresis for prolonged periods. MODURETIC,
with its
built-in potassium sparing agent, is especially indicated in those
conditions
where the positive effect on potassium balance is particularly
important.
MODURETIC may be used alone, or as an adjunct to other
antihypertensive
drugs. Since it enhances the action of these agents, the dosage of
these
antihypertensive drugs may need to be reduced to avoid the risk of an
excessive
drop in blood pressure.
4.2 DOSE AND METHOD OF ADMINISTRATION
MODURETIC tablets are available for oral use containing amiloride HCl
5 mg
and hydrochlorothiazide 50 mg.
Oedema of Cardiac Origin
MODURETIC may be started at a dosage of 1 or 2 tablets a day. Dosage
may
be increased if necessary, but must not exceed four tablets a day. The
optimal
MODURETIC – Data Sheet
Page 2 of 16
dosage is determined by the diuretic response and the serum potassium
level.
Once an initial diuresis has been achieved, reduction in dosage should
be
attempted
for
maintenance
therapy.
Maintenance
therapy
may
be
on
an
intermittent basis.
Hypertension
The usual dosage is one or two tablets given once a day or in divided
doses. The
dosage may be increased if necessary, but must not exceed four tablets
a day.
Hepatic Cirrhosis with Ascites (see