IDAMAN PHARMA MAGNESIUM TRISILICATE TABLET COMPOUND

Țară: Malaezia

Limbă: engleză

Sursă: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ingredient activ:

Magnesium Trisilicate; Aluminium hydroxide

Disponibil de la:

IDAMAN PHARMA MANUFACTURING SDN BHD

INN (nume internaţional):

Magnesium Trisilicate; Aluminium hydroxide

Unități în pachet:

30 Tablets

Produs de:

IDAMAN PHARMA MANUFACTURING SDN BHD

Prospect

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
IDAMAN PHARMA MAGNESIUM
TRISILICATE TABLET COMPOUND
Magnesium Trisilicate (250mg) and Dried Aluminium Hydroxide (120mg)
1
WHAT IS IN THIS LEAFLET
1.
What Idaman Pharma
Magnesium
Trisilicate Tablet Compound is used
for
2.
How Idaman Pharma
Magnesium
Trisilicate Tablet Compound works
3.
Before you use Magnesium Trisilicate
Tablet Compound
4.
How to use Idaman Pharma
Magnesium Trisilicate Tablet
Compound
5.
While you are using Idaman Pharma
Magnesium Trisilicate Tablet
Compound
6.
Side Effects
7.
Storage and Disposal of Idaman
Pharma
Magnesium Trisilicate Tablet
Compound
8.
Product Description
9.
Product Registration Holder and
Manufacturer
10.
Date of Revision
WHAT IDAMAN PHARMA MAGNESIUM
TRISILICATE TABLET COMPOUND IS USED FOR
Idaman Pharma
Magnesium Trisilicate
Tablet Compound contains a group of
medicine called antacids. This medicine is
indicated for following treatments: -
•
For symptomatic relief of stomach upset
associated with hyperacidity (heart burn,
acid indigestion and sour stomach).
•
For hyperacidity associated with gastric
and duodenal ulcers.
•
For symptomatic treatment of
gastroesophageal reflux disease (long
term condition where acid from the
stomach comes up into the esophagus).
HOW IDAMAN PHARMA MAGNESIUM
TRISILICATE TABLET COMPOUND WORKS
Idaman Pharma
Magnesium Trisilicate
Tablet Compound is a medicine that helps
correct the pH balance in the stomach. The
stomach has its own natural acids and
sometimes these acids become too much
and it is become too acidic.
Idaman Pharma
Magnesium Trisilicate
Tablet Compound works to neutralize or
buffer existing quantities of stomach acid
and reduces acid concentration within the
lumen of the oesophagus.
BEFORE YOU USE IDAMAN PHARMA
MAGNESIUM TRISILICATE TABLET
COMPOUND
-
_When you must not use it _
Idaman Pharma
Magnesium Trisilicate
Tablet Compound should not be given to
patients with following conditions:
• In patients with kidney problem.
• To young children (up to 6 years of age),
unless prescr

Caracteristicilor produsului

IDAMAN PHARMA MANUFACTURING IDAMAN PHARMA MAGNESIUM TRISILICATE TABLET
COMPOUND
DESCRIPTION
Round, flat, bevel edged tablets and scored on
one
side.
Colour:
W
hite
EACH TABLET
CONTAINS:
Magnesium Trisilicate 250
mg
Dried Aluminium Hydroxide
120
mg
_Preservative: _
Sodium Benzoate: 0.27mg ROUTE OF ADMINISTRATION
Oral PHARMACODYNAMICS
Magnesium Trisilicate and Dried Aluminium Hydroxide are both
slow acting antacids and absorption from the gut of breakdown
products is very limited. The action is virtually entirely the
inactivation of gastric acid and the symptomatic relief in gastric
hyper acidic peptic ulcers.
The reaction of the trisilicate is slow and prolonged, and the silica
formed is in the gelatinous colloidal state. The antacid action is
accordingly slow in onset but it is prolonged and powerful. The
absorbent properties of the product are possibly due to the
formation of the silica gel, which provides a protective coating
over
the
walls
of
the
stomach.
Aluminium
Hydroxide
has
neutralising
and
absorbent
actions.
It
does
not
completely
neutralise the stomach contents, but the pH achieved (3.4 to 4.0)
is sufficient to inhibit the proteolytic action of pepsin. There is
also some evidence that the aluminium ion may inhibit pepsin
action independently of its pH effect.
PHARMACOKINETICS
Aluminium and Magnesium ions are not completely absorbed.
Unreacted insoluble antacids pass through the intestines largely
as such and are excreted in the faeces. The reacted portion of the
antacids enters the intestine in the form of the cation. In the
intestine, some of the cation is absorbed; that which is absorbed
has
the
same
effect
on
the
systemic
bicarbonate
pool
as
an equivalent amount of NaHCO
3
because an equivalent amount
of HCO
3
returns to the systemic bicarbonate pool. Unabsorbed
cation does not spare enteric NaHCO
3
because an equivalent
amount of HCO
3
or CO
2
is consumed in the formation of insoluble
Hydroxides or Carbonates. Al
3+
may be thought of as reacting
with CO3
2
' to form an unstable AI
2
(CO2)
3
intermed