EPHEDRINE SULFATE INJECTION USP SOLUTION

Țară: Canada

Limbă: engleză

Sursă: Health Canada

Ingredient activ:

EPHEDRINE SULFATE

Disponibil de la:

EUGIA PHARMA INC.

Codul ATC:

C01CA26

INN (nume internaţional):

EPHEDRINE

Dozare:

50MG

Forma farmaceutică:

SOLUTION

Compoziție:

EPHEDRINE SULFATE 50MG

Calea de administrare:

INTRAVENOUS

Unități în pachet:

100

Tip de prescriptie medicala:

Ethical

Rezumat produs:

Active ingredient group (AIG) number: 0104862001; AHFS:

Statutul autorizaţiei:

APPROVED

Data de autorizare:

2023-01-09

Caracteristicilor produsului

Page 1 of 6
PRESCRIBING INFORMATION
EPHEDRINE SULFATE INJECTION USP
50 mg / mL
Sterile Solution for Subcutaneous, Intravenous or Intramuscular
administration
Sympathomimetic
Control Number: 269895
Date
of
Preparation:
January
09, 2023
Eugia
Pharma Inc.
3700 Steeles Avenue
West,
Suite
402
Woodbridge
Ontario, L4L 8K8
Canada
Page 2 of 6
EPHEDRINE SULFATE INJECTION USP
CLINICAL PHARMACOLOGY
Ephedrine is an adrenergic drug which exerts peripheral effects
resembling those of
epinephrine
and central effects resembling those of the amphetamines. Ephedrine
produces a
more sustained
action but is less potent than epinephrine.
It
stimulates both α and β
receptors and its
peripheral actions are due partly to norepinephrine release and partly
to direct
effects on receptors.
Ephedrine stimulates the heart, elevating the systolic and usually the
diastolic blood pressure. Its
vasopressor effect results largely from increased cardiac output
and
to a
lesser extent from
peripheral vasoconstriction. Ephedrine produces relaxation of
bronchial muscle which is more
sustained but less pronounced than that produced by
epinephrine. It also stimulates the central
nervous system to a greater extent than epinephrine
but its central action is less potent than that of
the amphetamines. The central effects of
ephedrine are overshadowed to a large extent by its
peripheral actions. It produces
sympathomimetic effects when administered orally, parenterally or
topically.
INDICATIONS
Ephedrine is used as a bronchodilator in the symptomatic treatment of
mild bronchial asthma
and
reversible bronchospasm which may occur in association with chronic
bronchitis,
emphysema, and
other obstructive pulmonary diseases.
Ephedrine is also used parenterally to produce cardiac stimulation and
vasoconstriction as
an
adjunct to correct hemodynamic imbalances, in the treatment of shock
which persists after
adequate
fluid volume replacement. (See PRECAUTIONS AND CONTRAINDICATIONS.)
Individual
hemodynamic abnormalities must be identified and monitored so that
therapy