EPHEDRINE SULFATE INJECTION USP SOLUTION

Țară: Canada

Limbă: engleză

Sursă: Health Canada

Ingredient activ:

EPHEDRINE SULFATE

Disponibil de la:

AURO PHARMA INC

Codul ATC:

C01CA26

INN (nume internaţional):

EPHEDRINE

Dozare:

50MG

Forma farmaceutică:

SOLUTION

Compoziție:

EPHEDRINE SULFATE 50MG

Calea de administrare:

SUBCUTANEOUS

Unități în pachet:

100

Tip de prescriptie medicala:

Ethical

Rezumat produs:

Active ingredient group (AIG) number: 0104862001; AHFS:

Statutul autorizaţiei:

APPROVED

Data de autorizare:

2022-08-17

Caracteristicilor produsului

Page 1 of 6
PRESCRIBING INFORMATION
EPHEDRINE SULFATE INJECTION USP
50 mg / mL
Sterile Solution
for Subcutaneous, Intravenous or Intramuscular administration
Sympathomimetic
Auro Pharma Inc.
3700 Steeles Avenue West,
Suite # 402 Woodbridge,
Ontario, L4L 8K8,
Canada.
Control number: 240861
Date of Preparation:
August 16, 2022
Page 2 of 6
EPHEDRINE SULFATE INJECTION USP
CLINICAL PHARMACOLOGY
Ephedrine is an adrenergic drug which exerts peripheral
effects resembling
those of
epinephrine
and central effects resembling
those of the amphetamines. Ephedrine produces a
more sustained
action but is less potent than epinephrine.
It stimulates
both α and β
receptors and its
peripheral actions are due partly to norepinephrine
release and partly to direct
effects on receptors.
Ephedrine stimulates the heart, elevating the systolic and usually the
diastolic
blood pressure. Its
vasopressor effect results largely from increased cardiac output
and to a lesser extent from
peripheral vasoconstriction.
Ephedrine produces relaxation of
bronchial muscle which is more
sustained
but less pronounced
than that produced by
epinephrine.
It also stimulates
the central
nervous system to a greater extent than epinephrine
but its central action is less potent than that of
the amphetamines.
The central effects of
ephedrine
are overshadowed to a large extent by its
peripheral actions. It produces
sympathomimetic
effects when administered orally, parenterally or
topically.
INDICATIONS
Ephedrine is used as a bronchodilator
in the symptomatic treatment of mild bronchial
asthma
and
reversible bronchospasm which may occur in association with chronic
bronchitis,
emphysema, and
other obstructive pulmonary diseases.
Ephedrine
is also used parenterally
to produce cardiac stimulation
and vasoconstriction
as
an
adjunct to correct hemodynamic
imbalances, in the treatment of shock which persists after
adequate
fluid volume replacement. (See PRECAUTIONS AND CONTRAINDICATIONS.)
Individua l
hemodynamic
abnormalities
must be identified
and monitored
so that the