urobiotic- oxytetracycline hydrochloride, sulfamethizole and phenazopyridine hydrochloride capsule

País: Estados Unidos

Língua: inglês

Origem: NLM (National Library of Medicine)

Ingredientes ativos:

oxytetracycline hydrochloride (UNII: 4U7K4N52ZM) (oxytetracycline - UNII:X20I9EN955, oxytetracycline - UNII:X20I9EN955, oxytetracycline - UNII:X20I9EN955), sulfamethizole (UNII: 25W8454H16) (sulfamethizole - UNII:25W8454H16, sulfamethizole - UNII:25W8454H16, sulfamethizole - UNII:25W8454H16), phenazopyridine hydrochloride (UNII: 2IUY41693Z) (phenazopyridine - UNII:, phenazopyridine - UNII:, phenazopyridine - UNII:)

Disponível em:

Roerig

DCI (Denominação Comum Internacional):

oxytetracycline hydrochloride, sulfamethizole and phenazopyridine hydrochloride

Forma farmacêutica:

CAPSULE

Via de administração:

ORAL

Tipo de prescrição:

PRESCRIPTION DRUG

Indicações terapêuticas:

Based on a review of this drug by the National Academy of Sciences-National Research Council and/or other information, FDA has classified the indications as follows: "Lacking substantial evidence of effectiveness as a fixed combination": Urobiotic-250 is indicated in the therapy of a number of genitourinary infections caused by susceptible organisms. These infections include the following: pyelonephritis, pyelitis, ureteritis, cystitis, prostatitis, and urethritis. Since both Terramycin and sulfamethizole provide effective levels in blood, tissue, and urine, Urobiotic-250 provides a multiple antimicrobial approach at the site of infection. Both antibacterial components are active against the most common urinary pathogens, including Escherichia coli, Pseudomonas aeruginosa, Aerobacter aerogenes, Streptococcus faecalis, Streptococcus hemolyticus , and Micrococcus pyogenes . Urobiotic-250 is particularly useful in the treatment of infections caused by bacteria more sensitive to the combination than to either com

Características técnicas

UROBIOTIC- OXYTETRACYCLINE HYDROCHLORIDE, SULFAMETHIZOLE AND
PHENAZOPYRIDINE
HYDROCHLORIDE CAPSULE
ROERIG
----------
UROBIOTIC -250
CAPSULES
EACH CAPSULE CONTAINS
OXYTETRACYCLINE HYDROCHLORIDE EQUIVALENT TO. . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . 250 MG OXYTETRACYCLINE
SULFAMETHIZOLE . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . 250 MG
PHENAZOPYRIDINE HYDROCHLORIDE . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . 50 MG
Inert ingredients in the formulation are: hard gelatin capsules (which
may contain Green 3, Yellow 6,
Yellow 10 and other inert ingredients); magnesium stearate; sodium
lauryl sulfate; starch.
ACTIONS
Urobiotic-250 is a product designed for use specifically in urinary
tract infections.
Terramycin (oxytetracycline HCl) is a widely used antibiotic with
clinically proved activity against
gram-positive and gram-negative bacteria, rickettsiae, spirochetes,
large viruses, and certain protozoa.
Terramycin is well tolerated and well absorbed after oral
administration. It diffuses readily through the
placenta and is present in the fetal circulation. It diffuses into the
pleural fluid, and under some
circumstances, into the cerebrospinal fluid. Oxytetracycline HCl
appears to be concentrated in the
hepatic system and is excreted in the bile. It is excreted in the
urine and in the feces, in high
concentrations, in a biologically active form.
Sulfamethizole is a chemotherapeutic agent active against a number of
important gram-positive and
gram-negative bacteria. This sulfonamide is well absorbed, has a low
degree of acetylation, and is
extremely soluble. Because of these features and its rapid renal
excretion, sulfamethizole has a low
order of toxicity and provides prompt and high concentrations of the
active drug in the urinary tract.
Phenazopyridine is an orally absorbed agent which produces prompt and
effective local analgesia and
relief of urinary symptoms by virtue of its rapid excretio