SODIUM CHLORIDE injection

País: Estados Unidos

Língua: inglês

Origem: NLM (National Library of Medicine)

Ingredientes ativos:

SODIUM CHLORIDE (UNII: 451W47IQ8X) (SODIUM CATION - UNII:LYR4M0NH37, CHLORIDE ION - UNII:Q32ZN48698)

Disponível em:

Cardinal Health 107, LLC

Via de administração:

INTRAVENOUS

Tipo de prescrição:

PRESCRIPTION DRUG

Indicações terapêuticas:

Sodium Chloride Injection, USP, 0.9% preparations are indicated for diluting or dissolving drugs for intramuscular, intravenous or subcutaneous injection according to instructions of the manufacturer of the drug to be administered. Sodium Chloride Injection, USP, 0.9% is also indicated for use in flushing of intravenous catheters.

Resumo do produto:

Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows: NDC# Strength Available over bagged with 5 x 10 mL Single Dose Vials in a bag 55154-9357-5 0.9% (90 mg per 10 mL) (9 mg per mL) Preservative Free. Discard unused portion. Use only if solution is clear and seal intact. Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature].

Status de autorização:

Abbreviated New Drug Application

Características técnicas

SODIUM CHLORIDE- SODIUM CHLORIDE INJECTION
CARDINAL HEALTH 107, LLC
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SODIUM CHLORIDE INJECTION, USP
0.9%
DESCRIPTION:
Sodium Chloride Injection, USP, 0.9% is a sterile, nonpyrogenic
solution. The osmolarity
is 300 mOsmol per liter (calculated).
Each mL contains: Sodium chloride 9 mg; Water for Injection q.s. It
contains no
bacteriostat, antimicrobial agent or added buffer and is supplied only
in single dose
containers. Hydrochloric acid and/or sodium hydroxide may have been
added for pH
adjustment (pH 4.5-7.0).
Sodium chloride occurs as colorless cubic crystals or white
crystalline powder and has a
saline taste. Sodium chloride is freely soluble in water. It is
soluble in glycerin and
slightly soluble in alcohol.
The empirical formula for sodium chloride is NaCl and the molecular
weight is 58.44.
CLINICAL PHARMACOLOGY:
Sodium chloride in water dissociates to provide sodium (Na
) and chloride (Cl
) ions.
These ions are normal constituents of the body fluids (principally
extracellular) and are
essential for maintaining electrolyte balance.
The distribution and excretion of sodium (Na
) and chloride (Cl
) are largely under the
control of the kidney which maintains a balance between intake and
output.
The small volume of fluid and amount of sodium chloride provided by
Sodium Chloride
Injection, USP, 0.9%, when used only as a vehicle for parenteral
injection of drugs, is
unlikely to exert a significant effect on fluid and electrolyte
balance except possibly in
very small infants.
Water is an essential constituent of all body tissues and accounts for
approximately
70% of total body weight. Average normal adult daily requirement
ranges from two to
three liters (1 to 1.5 liters each for insensible water loss by
perspiration and urine
production).
Water balance is maintained by various regulatory mechanisms. Water
distribution
depends primarily on the concentration of electrolytes in the body
compartments and
sodium (Na
) plays a major role in maintaining physiologic equilibrium.
INDICATIONS AND USAGE:
Sodium Ch