RESINCALCIO ORAL POWDER

País: Malásia

Língua: inglês

Origem: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ingredientes ativos:

CALCIUM POLYSTYRENE SULFONATE

Disponível em:

THE ZYFAS MEDICAL CO.,

DCI (Denominação Comum Internacional):

CALCIUM POLYSTYRENE SULFONATE

Unidades em pacote:

26Pieces Pieces; 100 Sachets

Fabricado por:

LABORATORIOS RUBIO, S.A

Características técnicas

RESINCALCIO
Calcium polystyrene sulphonate
FORMULA PER 100 G
Calcium polystyrene sulphonate (I.N.N.) 99.75 g
Excipients (Vanilla essence) 0.25g
DESCRIPTION: Brown or gilded fine powder, vanillin flavoured.
PROPERTIES
The action mechanism of the resin that we present, has its basis i n t
h e exchange
of calcium ions in plasma, for potassium. This exchange occurs in the
intestine
by an osmotic process. Thus it can be understood that in the organism,
via the
administration of this resin and its elimination in the faeces, it
removes the
potassium that it carries, until the plasma level reaches that which
is believed
to be convenient.
PHARMACOLOGICAL PROPERTIES
PHARMACODYNAMIC PROPERTIES
Pharmacotherapeutic group: V03AE Drugs for treatment of hyperkalemia.
Mechanism of action: calcium polystyrene sulphonate is a
cation-exchange resin
which acts in the intestine, exchanging two potassium cations for each
calcium
cation.
PHARMACOKINETICS PROPERTIES
Absorption: calcium polystyrene sulphonate is not absorbed in the
gastrointestinal
tract. Digestive juices do not degrade resin.
Metabolism: calcium polystyrene sulphonate is not metabolised. Resin
remains
unchanged. Excretion: Resin is excreted in the faeces.
INDICATIONS
RESINCALCIO powder for oral suspension is indicated in the treatment
and prevention
of hyperpotassaemia.
RECOMMENDED DOSE
Dose should be prescribed and under medical control, being usually:
Adults:
The recommended dose is 15 g up to three or four times a day suspended
in
water or sugared water. It should not be given in fruit juices that
have high potassium
content.
Children:
Acute hyperkalaemia: Recommended dose is up to 1 g/Kg body-weight/day,
in divided doses. Maintenance: Recommended dose is 500 mg/Kg
bodyweight/ day, in
divided doses.
As with sodium polystyrene sulphonate, administer calcium polystyrene
sulphonate at
least 3 hours before or 3 hours after other oral medications. Patients
with
gastroparesis may require a 6-hour separation.
CONTRAINDICATIONS
The administration of calcium polystyrene sulpho