País: Estados Unidos
Língua: inglês
Origem: NLM (National Library of Medicine)
LUFENURON (UNII: 1R754M4918) (LUFENURON - UNII:1R754M4918)
Novartis Animal Health US, Inc.
LUFENURON
LUFENURON 100 mg in 1 mL
PRESCRIPTION
New Animal Drug Application
PROGRAM 6 MONTH INJECTABLE FOR CATS- LUFENURON INJECTION, SUSPENSION NOVARTIS ANIMAL HEALTH US, INC. ---------- PROGRAM 6 MONTH INJECTABLE FOR CATS 6 Month Injectable for Cats The six-month injection that controls flea populations in cats. CAUTION U.S. Federal law restricts this drug to use by or on the order of a licensed veterinarian. DES CRIPTION PROGRAM® (lufenuron) 6 Month Injectable for Cats is available in two syringe sizes for subcutaneous administration to cats and kittens according to their weight (See Dosage). Each preloaded syringe is formulated to provide 4.54 mg/pound (10 mg/kg) body weight of lufenuron. The active ingredient of PROGRAM 6 Month Injectable for Cats is lufenuron, a benzoylphenyl-urea derivative with the following chemical composition: N-[2,5-dichloro-4-(1,1,2,3,3,3,-hexafluoropropoxy)- phenylaminocarbonyl]-2,6-difluorobenzamide. Benzoylphenyl-urea compounds, including lufenuron, are classified as insect development inhibitors (IDIs). MODE OF ACTION Lufenuron, the active ingredient of PROGRAM 6 Month Injectable for Cats, is an insect development inhibitor which breaks the flea life cycle by inhibiting egg development. Lufenuron’s mode of action is interference with chitin synthesis, polymerization and deposition. Lufenuron has no effect on adult fleas. After biting a lufenuron-treated cat, the female flea ingests a blood meal containing lufenuron which is subsequently deposited in her eggs. Lufenuron prevents flea eggs from hatching and developing into adults and thus controls flea populations by breaking the life cycle. (See Efficacy.) INDICATIONS PROGRAM 6 Month Injectable for Cats is indicated for use in cats, six weeks of age and older, for the control of flea populations. Lufenuron controls flea populations by preventing the development of flea eggs and does not kill adult fleas. Concurrent use of insecticides may be necessary for adequate control of adult fleas. WARNING DO NOT USE IN DOGS. A SEVERE LOCAL REACTION MAY OCCUR IN DOGS THAT IS NOT SEEN IN CATS. PRECAUTIONS The safe Leia o documento completo