LORIDIN RAPITAB 10MG

País: Malásia

Língua: inglês

Origem: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ingredientes ativos:

LORATADINE

Disponível em:

THE ZYFAS MEDICAL CO.,

DCI (Denominação Comum Internacional):

LORATADINE

Unidades em pacote:

100Tablet Tablets

Fabricado por:

CADILA HEALTHCARE LIMITED

Folheto informativo - Bula

_Consumer Medication Information Leaflet (RiMUP) _
LORIDIN RAPITAB 10MG TABLET
Loratadine (10mg)
WHAT IS IN THIS LEAFLET
1.
What LORIDIN RAPITAB
10mg TABLET is used for
2.
How LORIDIN RAPITAB
10mg TABLET works
3.
Before you use LORIDIN
RAPITAB 10mg TABLET
4.
How to use LORIDIN
RAPITAB 10mg TABLET
5.
While you are using it
6.
Side effects
7.
Storage and disposal of
LORIDIN RAPITAB 10mg
TABLET
8.
Product description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
WHAT
LORIDIN
RAPITAB
10MG
TABLET IS USED FOR
LORIDIN RAPITAB TABLET is used in
the treatment of seasonal allergic rhinitis
(inflammation
of
mucous
membrane
inside the nose), perennial (throughout
the year) rhinitis, urticaria (a red, raised,
itchy
rash)
and
allergic
dermatologic
(skin) disorders.
Ask your doctor or pharmacist for advice
before taking any medicine.
-
_Before you start to use it _
_ _
Talk
to
your
doctor,
pharmacist
or
nurse
before
taking
LORIDIN
RAPITAB 10mg TABLET if:
_ _
•
you have liver disease.
_ _
_ _
•
you are scheduled to have any skin
tests
for
allergies.
Do
not
take
LORIDIN
RAPITAB
10mg
TABLET for two days before having
these tests. This is because it may
affect the test results.
_ _
If any of the above apply to you (or you
are
not
sure),
talk
to
your
doctor,
pharmacist
or
nurse
before
taking
LORIDIN RAPITAB 10mg TABLET.
-
_Taking other medicines _
_ _
Tell your doctor, pharmacist or nurse if
you are taking, have recently taken or
might take any other medicines. This
includes
medicines
taken
without
a
prescription
from
a
pharmacy,
supermarket or health food shop.
-
_How long to use it _
_ _
Continue taking LORIDIN RAPITAB
10mg TABLET for as long as your
doctor recommends.
_ _
-
_If you forget to use it _
_ _
•
If you forget to take your dose, take it
as
soon
as
you
remember,
then
continue to take it as usual.
•
If it is almost time for your next dose,
wait until then to take the medicine
and skip the missed dose.
•
Do not take a double dose to make
up for a forgotten dose.
-
_If you use too much (over

Características técnicas

For The use of a Registered Medical Practitioner or a Hospital or a
Laboratory only.
LORATADINE DISPERSIBLE TABLETS
LORIDIN RAPITAB
COMPOSITION:
Each uncoated dispersible tablet of Loridin Rapitab contains:
Loratadine 10 mg
DESCRIPTION:
White to off-white, smooth, round, flavoured, uncoated tablets with
bevelled edges having
breakline on one side and plain on the other.
Loridin Rapitab Tablets disintegrate in the mouth within seconds after
placement on the
tongue, allowing its contents to be subsequently swallowed with or
without water, thereby
greatly enhancing patient compliance.
CLINICAL PHARMACOLOGY:
Loratadine is a competitive blocker of peripheral histamine H1
receptors. It has a weak
anticholinergic & alpha-adrenoceptor blocking action. Onset of
antihistaminic action with
Loratadine, as measured by wheal and flare suppression, is apparent
within first hour of
administration, and is sustained up to 24 hours. Loratadine 10 to 20
mg exhibits a protective
effect on airways in response to inhaled histamine challenge in
patient with asthma. The
antiallergic activity of loratadine has been demonstrated in human
using cutaneous, nasal
challenge and conjunctival provocation tests.
Loratadine is well absorbed after oral administration with peak
concentrations of 24.3 and
30.5 mcg/L occurring in 1 and 1.5 hours alter ingestion of 4.0 mg
drug. Loratadine is 97 to
99% plasma protein bound and has a large volume of distribution
(119L/kg). Loratadine is
rapidly metabolised and an active metabolite descarboethoxyloratadine
(DCL) is formed in
vivo. Plasma elimination half-lives of loratadine and DCL range from
7.8 to 11 hours and 17
to 24 hours respectively. While loratadine is excreted into breast
milk, the amount of
administered drug appearing in the milk is minimal. The dosage
adjustments are not required
in patients with renal dysfunction and elderly.
Pharmacokinetic studies have showed that Loridin Rapitab tablets
provide plasma
concentrations of loratadine and descarboethoxyloratadine similar to
those achieved with
p