HYOSCYAMINE SULFATE tablet

País: Estados Unidos

Língua: inglês

Origem: NLM (National Library of Medicine)

Ingredientes ativos:

HYOSCYAMINE SULFATE (UNII: F2R8V82B84) (HYOSCYAMINE - UNII:PX44XO846X)

Disponível em:

Vilvet Pharmaceuticals Inc

DCI (Denominação Comum Internacional):

HYOSCYAMINE SULFATE

Composição:

HYOSCYAMINE SULFATE 0.125 mg

Via de administração:

SUBLINGUAL

Tipo de prescrição:

PRESCRIPTION DRUG

Indicações terapêuticas:

Hyoscyamine sulfate is indicated whenever antispasmodic or anticholinergic therapy is desired. The high degree of purity allows effective action at very low dosage, with a minimal incidence of unwanted side effects.

Resumo do produto:

Hyoscyamine Sulfate Sublingual Tablets 0.125 mg are white, pentagon shaped tablets debossed "VIP107" on one side in bottles of 100ct, NDC 71186-009-25. Store at controlled room temperature 20°- 25°C (68° - 77°F); excursions permitted to 15°- 30°C (59°- 86°F). Please refer to current USP. Dispense in tight, light-resistant container as defined in USP/NF with a child-resistant closure. KEEP THIS AND ALL DRUGS OUT OF REACH OF CHILDREN.

Status de autorização:

unapproved drug other

Características técnicas

HYOSCYAMINE SULFATE- HYOSCYAMINE SULFATE TABLET
VILVET PHARMACEUTICALS INC
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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HYOSCYAMINE SULFATE SUBLINGUAL TABLETS 0.125 MG
Rx only.
DESCRIPTION
Hyoscyamine Sulfate Sublingual Tablets 0.125 mg are white, pentagon
shaped tablets debossed
"VIP107" on one side.
Hyoscyamine Sulfate Sublingual tablets contain 0.125 mg Hyoscyamine
sulfate formulated for oral
administration. Hyoscyamine sulfate is one of the principal
anticholinergic/antispasmodic components
of belladonna alkaloids. The molecular formulate is (C
H NO ) ·H SO ·2H O and the molecular
weight is 712.85. Chemically, it is benzeneacetic acid,
α-hydroxymethyl)-8-mehtyl-8-azabicyclo [3.2.1]
oct-3-yl ester, [3(S)-endo]-, sulfate (2:1), dehydrate with the
following structural formula:
Each tablet also contains as inactive ingredients: mannitol,
microcrystalline cellulose, croscarmellose
sodium and magnesium stearate.
CLINICAL PHARMACOLOGY
Hyoscyamine sulfate inhibits specifically the actions of acetylcholine
on structures innervated by
postganglionic cholinergic nerves and on smooth muscles that respond
to acetylcholine but lack
cholinergic innervation. These peripheral cholinergic receptors are
present in the autonomic effector
cells of the smooth muscle, cardiac muscle, the sinoatrial node, the
atrioventricular node, and the
exocrine glands. At therapeutic doses, it is completely devoid of any
action on autonomic ganglia.
Hyoscyamine sulfate inhibits gastrointestinal propulsive motility and
decreases gastric acid secretion.
Hyoscyamine sulfate also controls excessive pharyngeal, tracheal and
bronchial secretions.
Hyoscyamine sulfate is absorbed totally and completely by sublingual
administration as well as oral
administration. Once absorbed, Hyoscyamine sulfate disappears rapidly
from the blood and is
distributed throughout the entire body. The half-life of Hyoscyam