Dalacin C Phosphate Injection

País: Austrália

Língua: inglês

Origem: Department of Health (Therapeutic Goods Administration)

Ingredientes ativos:

Clindamycin phosphate

Disponível em:

Pfizer Australia Pty Ltd

Classe:

Medicine Registered

Folheto informativo - Bula

DALACIN
®
 C PHOSPHATE
INJECTION

_Clindamycin phosphate_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Dalacin C Phosphate
injection. It does not contain all the
available information.
It does not take the place of talking to
your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you being given Dalacin
C Phosphate injection against the
benefits this medicine is expected to
have for you.
Dalacin C Phosphate injection should
only be given to you by a health
professional.
IF YOU HAVE ANY CONCERNS ABOUT
USING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH YOUR
MEDICINE.
You may need to read it again.
WHAT DALACIN C
PHOSPHATE INJECTION IS
USED FOR
Dalacin C Phosphate injection is an
antibiotic. It is used to treat
infections in different parts of the
body caused by bacteria.
Dalacin C Phosphate works by
killing or stopping the growth of
bacteria causing your infection.
Dalacin C Phosphate will not work
against viral infections such as colds
or flu.
Dalacin C Phosphate injection is
recommended for patients who are
allergic to penicillin or patients for
whom, in the judgment of the doctor,
penicillin is inappropriate.
Your doctor may have prescribed
Dalacin C Phosphate injection for
another reason. Ask your doctor if
you have any questions about why
Dalacin C Phosphate injection has
been prescribed for you.
This medicine is available only with
a doctor's prescription.
Dalacin C Phosphate is not addictive.
BEFORE YOU ARE GIVEN
DALACIN C PHOSPHATE
INJECTION
_WHEN YOU MUST NOT BE GIVEN_
_DALACIN C PHOSPHATE_
_INJECTION_
YOU MUST NOT BE GIVEN DALACIN C
PHOSPHATE INJECTION:
1. IF YOU HAVE AN ALLERGY TO:
•
clindamycin or lincomycin
•
any of the other ingredients listed
at the end of this leaflet (see
'Product Description')
 Symptoms of an allergic reaction
may include skin rash, itching or
difficulty in breathing.
2. IF THE PACKAGING IS TORN OR
SHOWS SIGNS OF TAMPERING
3. AF

Características técnicas

PRODUCT INFORMATION 
DALACIN
® 
C PHOSPHATE 
CLINDAMYCIN INJECTION 
For Intramuscular and Intravenous Use 
DESCRIPTION 
DALACIN C Phosphate (clindamycin phosphate injection) is a sterile
solution of a water 
soluble ester of clindamycin and phosphoric acid which contains the
equivalent of 150 mg 
clindamycin base, 9.45 mg benzyl alcohol and
0.5 mg disodium edetate in each mL of water 
for injections.  Clindamycin is a semi-synthetic antibiotic produced
by a 
7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent
compound lincomycin. 
The MW of clindamycin phosphate is 504.96 and its structural formula
is represented below: 

CAS Number:  24729-96-2 
ACTION 
MICROBIOLOGY 
Although clindamycin phosphate is inactive _in vitro_, rapid _in
vivo_ hydrolysis converts this 
compound to the antibacterially active clindamycin. 
Clindamycin has been shown to have _in vitro_ activity against
isolates of the following 
organisms: 

Aerobic gram-positive cocci, including: 

_Staphylococcus aureus _

_Staphylococcus epidermidis _(penicillinase and non-penicillinase
producing strains) 
   When 
tested 
by 
_in vitro_ methods some staphylococcal strains, originally
resistant 
to erythromycin, rapidly develop resistance to clindamycin. 

_Streptococci_ (not Enterococcus faecalis) 

_Pneumococci _
Version: pfpdacpi10509 
Supersedes: pfpdacpi10208 
Commercial/Non commercial 
Page 1 of 10 

Anaerobic gram-negative bacilli, including: 

_Bacteroides_ species 

_Fusobacterium_ species 

Anaerobic gram-positive non-spore forming bacilli, including: 

_Propionibacterium  _

_Eubacterium _

_Actinomyces_ species 

Anaerobic and microaerophilic gram-positive cocci, including: 

_Peptococcus_ species 

_Peptostreptococcus_ species 
  Microaerophilic 
_streptococci_ 

_Clostridia_ 

_Clostridia_ are more resistant than most anaerobes to clindamycin.
 Most 
_C. perfringens_ a