CHLORDIAZEPOXIDE HYDROCHLORIDE/CLIDINIUM BROMIDE and capsule

País: Estados Unidos

Língua: inglês

Origem: NLM (National Library of Medicine)

Ingredientes ativos:

Chlordiazepoxide Hydrochloride (UNII: MFM6K1XWDK) (Chlordiazepoxide - UNII:6RZ6XEZ3CR)

Disponível em:

Avera McKennan Hospital

DCI (Denominação Comum Internacional):

Chlordiazepoxide Hydrochloride

Composição:

Chlordiazepoxide Hydrochloride 5 mg

Tipo de prescrição:

PRESCRIPTION DRUG

Status de autorização:

unapproved drug other

Características técnicas

CHLORDIAZEPOXIDE HYDROCHLORIDE/CLIDINIUM BROMIDE- CHLORDIAZEPOXIDE
HYDROCHLORIDE AND CLIDINIUM BROMIDE CAPSULE
AVERA MCKENNAN HOSPITAL
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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CHLORDIAZEPOXIDE HYDROCHLORIDE/
CLIDINIUM BROMIDE CAPSULES
_to control emotional_
_and somatic factors_
_in gastrointestinal disorders_
DESCRIPTION
Chlordiazepoxide Hydrochloride/Clidinium Bromide combines in a single
capsule formulation the
antianxiety action of chlordiazepoxide hydrochloride and the
anticholinergic/spasmolytic effects of
clidinium bromide, both exclusive developments of Roche research.
Each Chlordiazepoxide Hydrochloride/Clidinium Bromide capsule contains
5 mg chlordiazepoxide
hydrochloride, USP and 2.5 mg clidinium bromide, USP. Each capsule
also contains lactose
monohydrate, pregelatinized starch, talc, titanium dioxide, D&C Yellow
#10, FD&C Green #3 and
gelatin.
Chlordiazepoxide hydrochloride is a versatile, therapeutic agent of
proven value for the relief of
anxiety and tension. It is indicated when anxiety, tension or
apprehension are significant components of
the clinical profile. It is among the safer of the effective
psychopharmacologic compounds.
Chlordiazepoxide hydrochloride is
7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine 4-oxide
hydrochloride. A colorless, crystalline substance, it is soluble in
water. It is unstable in solution and the
powder must be protected from light. The molecular weight is 336.22.
The structural formula of
chlordiazepoxide hydrochloride is as follows:
Clidinium bromide is a synthetic anticholinergic agent which has been
shown in experimental and
clinical studies to have a pronounced antispasmodic and antisecretory
effect on the gastrointestinal tract.
Structurally clidinium bromide is:
ANIMAL PHARMACOLOGY & OR TOXICOLOGY
Chlordiazepoxide hydrochloride has been studied extensively in many
species of animals and these
studies