País: Estados Unidos
Língua: inglês
Origem: NLM (National Library of Medicine)
CHLORDIAZEPOXIDE HYDROCHLORIDE (UNII: MFM6K1XWDK) (CHLORDIAZEPOXIDE - UNII:6RZ6XEZ3CR), CLIDINIUM BROMIDE (UNII: 91ZQW5JF1Z) (CLIDINIUM - UNII:BO76JF850N)
Bryant Ranch Prepack
ORAL
PRESCRIPTION DRUG
Chlordiazepoxide HCl/Clidinium Bromide is indicated to control emotional and somatic factors in gastrointestinal disorders. Chlordiazepoxide HCl/Clidinium Bromide may also be used as adjunctive therapy in the treatment of peptic ulcer and in the treatment of the irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and acute enterocolitis. Chlordiazepoxide HCl/Clidinium Bromide is contraindicated in the presence of glaucoma (since the anticholinergic component may produce some degree of mydriasis) and in patients with prostatic hypertrophy and benign bladder neck obstruction. It is contraindicated in patients with known hypersensitivity to chlordiazepoxide hydrochloride and/or clidinium bromide. Withdrawal symptoms, similar in character to those noted with barbiturates and alcohol (convulsions, tremor, abdominal and muscle cramps, vomiting and sweating), have occurred following abrupt discontinuance of chlordiazepoxide. The more severe withdrawal symptoms have usually been limited to tho
Chlordiazepoxide HCl/Clidinium Bromide is available in light green opaque capsules, each containing 5 mg chlordiazepoxide hydrochloride and 2.5 mg clidinium bromide, in bottles of 100 (NDC 63629-2146-1), with LIBRAX® ICN imprinted on the body of the capsule. Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F). Keep out of reach of children. Dispense in a tight, light-resistant container as defined in USP/NF.
New Drug Application Authorized Generic
CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE- chlordiazepoxide hydrochloride and clidinium bromide capsule Bryant Ranch Prepack ---------- Medication Guide Chlordiazepoxide HCl/Clidinium Bromide capsules What is the most important information I should know about Chlordiazepoxide HCl/Clidinium Bromide? • Do not stop taking Chlordiazepoxide HCl/Clidinium Bromide without first talking to your healthcare provider. Stopping Chlordiazepoxide HCl/Clidinium Bromide suddenly can cause serious side effects. • Taking Chlordiazepoxide HCl/Clidinium Bromide with opioid medicines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, breathing problems (respiratory depression), coma and death. • Do not drive, operate heavy machinery, or do other dangerous activities until you know how Chlordiazepoxide HCl/Clidinium Bromide affects you. • Do not drink alcohol or take other drugs that may make you sleepy or dizzy while taking Chlordiazepoxide HCl/Clidinium Bromide without first talking to your healthcare provider. When taken with alcohol or drugs that cause sleepiness or dizziness, Chlordiazepoxide HCl/Clidinium Bromide may make your sleepiness or dizziness much worse. • Chlordiazepoxide HCl/Clidinium Bromide can cause abuse and dependence. • Do not stop taking Chlordiazepoxide HCl/Clidinium Bromide all of a sudden. Stopping Chlordiazepoxide HCl/Clidinium Bromide suddenly can cause seizures, shaking, stomach and muscle cramps, vomiting and sweating. • Physical dependence is not the same as drug addiction. Your healthcare provider can tell you more about the differences between physical dependence and drug addiction. What is Chlordiazepoxide HCl/Clidinium Bromide? • Chlordiazepoxide HCl/Clidinium Bromide is a prescription medicine that is used with other therapies for the treatment of: • stomach (peptic) ulcers • irritable bowel syndrome (IBS) • inflammation of the colon called acute enterocolitis • Chlordiazepoxide HCl/Clidinium Bromide contains Leia o documento completo
CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE- CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE CAPSULE BRYANT RANCH PREPACK ---------- CHLORDIAZEPOXIDE HCL/CLIDINIUM BROMIDE CAPSULES WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death (see WARNINGS and PRECAUTIONS). • • • DESCRIPTION Chlordiazepoxide HCl/Clidinium Bromide combines in a single capsule formulation the antianxiety action of chlordiazepoxide hydrochloride and the anticholinergic/spasmolytic effects of clidinium bromide. Each Chlordiazepoxide HCl/Clidinium Bromide capsule contains the active ingredients 5 mg chlordiazepoxide hydrochloride and 2.5 mg clidinium bromide. Each capsule also contains the inactive ingredients corn starch, lactose monohydrate, talc, methylparaben, propylparaben, potassium sorbate, D&C Yellow No. 10, FD&C Green No. 3, titanium dioxide, and gelatin. Chlordiazepoxide hydrochloride is a versatile, therapeutic agent of proven value for the relief of anxiety and tension. It is indicated when anxiety, tension or apprehension are significant components of the clinical profile. It is among the safer of the effective psychopharmacologic compounds. Chlordiazepoxide hydrochloride is 7-chloro-2-methylamino-5-phenyl-3H-1,4- benzodiazepine 4-oxide hydrochloride. A colorless, crystalline substance, it is soluble in water. It is unstable in solution and the powder must be protected from light. The molecular weight is 336.22. The structural formula of chlordiazepoxide hydrochloride is as follows: Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. Follow patients for signs and symptoms of respiratory depression and sedation. Clidinium bromide is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory ef Leia o documento completo