País: Malásia
Língua: inglês
Origem: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
AZITHROMYCIN DIHYDRATE
HOVID BERHAD
AZITHROMYCIN DIHYDRATE
30Tablet Tablets; 100Tablet Tablets; 60 Tablet Tablets; 30 Tablet Tablets; 6 Tablet Tablets
HOVID BERHAD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ AZIMAX 250MG TABLET Azithromycin 250mg 1 WHAT IS IN THIS LEAFLET? 1. What Azimax 250 mg Tablet is used for 2. How Azimax 250 mg Tablet works 3. Before you use Azimax 250 mg Tablet 4. How to take Azimax 250 mg Tablet 5. While you are using Azimax 250mg Tablet 6. Side effects 7. After using Azimax 250 mg Tablet 8. Product description 9. Manufacturer 10. Product Registration Holder 11. Date of revision WHAT AZIMAX 250 MG TABLET IS USED FOR Used to treat infections of the middle ear (otitis media) throat (strep throat) lungs (bronchitis) sinuses (sinusitis) chest (pneumonia) skin and soft tissue genitals caused by _Chlamydia _ _trachomatis_ . _ _ HOW AZIMAX 250 MG TABLET WORKS Azimax belongs to a group of antibiotics called macrolides. It acts on bacteria that cause infections by either killing them or stopping their growth. Azimax does not work against viral infection such as cold and flu. BEFORE YOU USE AZIMAX 250 MG TABLET _When you must not take it _ Do not take this medicine if you are allergic to azithromycin, any other macrolide or ketolide and any of the excipients used in this product. Your doctor will carefully consider your condition before giving you this medicine. _Before you start to take it _ Tell your doctor if: you have heart problems you have liver problems you have kidney problems you are pregnant, plan to get pregnant or breastfeeding you are taking medicines derived from ergot. _Taking other medicines _ Talk to your doctor or pharmacist if you are taking any other medicines in any form including any that you buy or obtained without a prescription. Some medicines interfere with this antibiotic. They include: antacids (for indigestion) warfarin (to prevent blood clots) terfenadine or astemizole (for skin allergies) cyclosporine (to prevent organ transplant rejection and to treat any overactive immune system problems) digoxin (to treat heart failure) ergotamine / dihydroergotami Leia o documento completo
AZIMAX-250 TABLET VIAZIxx-0 (MY)_2 DESCRIPTION Oblong, white film-coated tablet, bevel-edged, shallow convex with break bar on one side and ‘HOVID’ embossed on the other side. COMPOSITION Each film-coated tablet contains Azithromycin 250 mg. PHARMACODYNAMICS Azithromycin is an azalide antibiotic, part of the macrolide family of antibacterials. It binds to the 50S ribosomal subunit of the 70S ribosome of susceptible organisms, thereby inhibiting RNA-dependent protein synthesis. PHARMACOKINETICS Following oral administration, azithromycin is rapidly absorbed and widely distributed throughout the body; bioavailability is approximately 37%. The time taken to peak plasma levels is 2-3 hours. The plasma terminal elimination half-life closely reflects the tissue depletion half-life of 2 to 4 days. Protein binding varies with concentration: very low to moderate; approximately 7% at 1 µg/mL, to 50% at 0.02 to 0.05µg/mL. Azithromcyin concentrates intracellularly, resulting in tissue concentrations 10 to 100 times higher than those found in plasma or serum. Azithromcyin is highly concentrated in phagocytes and fibroblasts. Biotransformation occurs in liver, in which approximately 35% metabolized by demethylation. Over 50% of the dose is eliminated through biliary excretion as unchanged drug. INDICATIONS Azithromycin is indicated for the treatment of the following infections when known or likely to be due to one or more susceptible microorganisms: • bronchitis • community-acquired pneumonia • sinusitis • pharyngitis/tonsillitis • otitis media • skin and soft tissue infections • uncomplicated genital infections due to Chlamydia trachomatis CONTRAINDICATIONS • This medication should not be used when the patient is hypersensitive to azithromycin or other macrolides. • Risk-benefit should be considered when hepatic function impairment exists because biliary excretion is the major route of elimination. WARNING AND PRECAUTIONS • In the event of severe acute hypersensitivity reactions, such as anaphylaxis, Leia o documento completo