AMLODIPINE BESYLATE tablet AMLODIPINE BESYLATE tablet

País: Estados Unidos

Língua: inglês

Origem: NLM (National Library of Medicine)

Ingredientes ativos:

AMLODIPINE BESYLATE (UNII: 864V2Q084H) (AMLODIPINE - UNII:1J444QC288)

Disponível em:

DirectRX

DCI (Denominação Comum Internacional):

AMLODIPINE BESYLATE

Composição:

AMLODIPINE 5 mg

Via de administração:

ORAL

Tipo de prescrição:

PRESCRIPTION DRUG

Indicações terapêuticas:

- 1.1 Hypertension Amlodipine besylate tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including amlodipine besylate tablets. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program's Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC). Numerous antihypertensive drugs, from a va

Status de autorização:

Abbreviated New Drug Application

Características técnicas

AMLODIPINE BESYLATE- AMLODIPINE BESYLATE TABLET
AMLODIPINE BESYLATE- AMLODIPINE BESYLATE TABLET
DIRECTRX
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AMLODIPINE BESYLATE
INDICATIONS & USAGE SECTION
1.1 Hypertension
Amlodipine besylate tablets are indicated for the treatment of
hypertension, to lower
blood pressure. Lowering blood pressure reduces the risk of fatal and
nonfatal
cardiovascular events, primarily strokes and myocardial infarctions.
These benefits
have been seen in controlled trials of antihypertensive drugs from a
wide variety of
pharmacologic classes including amlodipine besylate tablets.
Control of high blood pressure should be part of comprehensive
cardiovascular risk
management, including, as appropriate, lipid control, diabetes
management,
antithrombotic therapy, smoking cessation, exercise, and limited
sodium intake. Many
patients will require more than one drug to achieve blood pressure
goals. For specific
advice on goals and management, see published guidelines, such as
those of the
National High Blood Pressure Education Program's Joint National
Committee on
Prevention, Detection, Evaluation, and Treatment of High Blood
Pressure (JNC).
Numerous antihypertensive drugs, from a variety of pharmacologic
classes and with
different mechanisms of action, have been shown in randomized
controlled trials to
reduce cardiovascular morbidity and mortality, and it can be concluded
that it is blood
pressure reduction, and not some other pharmacologic property of the
drugs, that is
largely responsible for those benefits. The largest and most
consistent cardiovascular
outcome benefit has been a reduction in the risk of stroke, but
reductions in
myocardial infarction and cardiovascular mortality also have been seen
regularly.
Elevated systolic or diastolic pressure causes increased
cardiovascular risk, and the
absolute risk increase per mmHg is greater at higher blood pressures,
so that even
modest reductions of severe hypertension can provide substantial
benefit. Relative
risk reduction from blood pressure reduction is similar across
populati