ALLERYL TABLET 4MG

País: Malásia

Língua: inglês

Origem: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ingredientes ativos:

CHLORPHENIRAMINE MALEATE

Disponível em:

IDAMAN PHARMA MANUFACTURING SDN BHD

DCI (Denominação Comum Internacional):

CHLORPHENIRAMINE MALEATE

Unidades em pacote:

100 Tablets; 1000 Tablets

Fabricado por:

IDAMAN PHARMA MANUFACTURING SDN BHD

Folheto informativo - Bula

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
ALLERYL TABLET
Chlorpheniramine Maleate (4mg)
1
WHAT IS IN THIS LEAFLET
1.
What Alleryl Tablet 4mg is used
for
2.
How Alleryl Tablet 4mg works
3.
Before you use Alleryl Tablet 4mg
4.
How to use Alleryl Tablet 4mg
5.
While you are using Alleryl Tablet
4mg
6.
Side Effects
7.
Storage
and
Disposal
of
Alleryl
Tablet 4mg
8.
Product Description
9.
Product
Registration
Holder
&
Manufacturer
10.
Date of Revision
WHAT ALLERYL TABLET 4MG IS USED FOR
Alleryl Tablet belongs to a group of
medicines called antihistamines.
Alleryl
Tablet
4mg
contains
chlorpheniramine
maleate
which
is
used to treat the following:
•
Symptomatic treatment of perennial
(throughout the year) and seasonal
allergic rhinitis (inflammation of the
membranes
inside
of
the
nose.),
vasomotor
rhinitis
(nonallergic)
and
allergic
conjunctivitis
(eye
inflammation)
due to inhalant allergens and foods.
•
Symptomatic
treatment
of
skin
itching
associated
with
allergic
reactions and of mild, uncomplicated
symptoms of urticaria (a red raised,
itchy
rash
on
the
skin.)
and
angioedema (swelling of deeper skin
tissues).
•
May be used in combination with a
decongestant (Pseudoephedrine) for
the
temporary
relief
of
nasal
and
sinus congestion associated with the
common cold and allergic rhinitis.
HOW ALLERYL TABLET 4MG WORKS
Alleryl Tablet works by blocking a
certain natural substance (histamine)
that
your
body
makes
during
an
allergic
reaction.
Histamine
is
a
chemical which causes the symptoms
of allergies.
The
antimuscarinic
actions
of
most
antihistamines provide a drying effect
on the nasal mucosa.
BEFORE YOU USE ALLERYL TABLET 4MG
_-When you must not use it _
Do not take Alleryl Tablet 4mg if
you are:
•
Allergic
to
chlorpheniramine
maleate or
any
ingredients
in
the
product.
•
Taking drugs for depression known
as
Monoamine
Oxidase
Inhibitors
(MAOIs).
•
Having
lower
respiratory
diseases,
including asthma.
_Pregnancy and breast-feeding _
Do not take Alleryl Tablet 4mg if you
are pregnant, trying to get pregnant

Características técnicas

IDAMAN PHARMA MANUFACTURING ALLERYL TABLET 4MG
DESCRIPTION
Clean, dry, round, flat, bevel-edged, scored on one side and pink
tablet.
Each tablet contains Chlorpheniramine Maleate 4mg
Source of lactose: Bovine
ROUTE OF ADMINISTRATION
Oral
PHARMACODYNAMICS
Chlorpheniramine is a potent antihistamine (H1-antagonist).
Antihistamines diminish or abolish the actions of histamine in the
body by competitive reversible blockade of histamine H1-receptor
sites on tissues. Chlorpheniramine also has anticholinergic activity.
Antihistamines
act
to
prevent
the
release
of
histamine,
prostaglandins and leukotrienes and have been shown to prevent
the
migration
of
inflammatory
mediators.
The
actions
of
chlorpheniramine
include
inhibition
of
histamine
on
smooth
muscle, capillary permeability and hence reduction of oedema and
wheal in hypersensitivity reactions such as allergy and anaphylaxis.
PHARMACOKINETICS
Chlorpheniramine is well absorbed from the gastro-intestinal tract,
following
oral
administration.
The
effects
develop
within
30
minutes, are maximal within 1 to 2 hours and last 4 to 6 hours. The
plasma half-life has been estimated to be 12 to 15 hours.
Chlorpheniramine
is
metabolised
to
the
monodesmethyl
and
didesmethyl derivatives. About 22% of an oral dose is excreted
unchanged in the urine.
INDICATIONS
This medicine is indicated for symptomatic control of all allergic
conditions
responsive
to
antihistamines,
including
hay
fever,
vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy,
drug and serum reactions, insect bites and itch associated with
chickenpox.
Temporary
relief
of
nasal
and
sinus
congestion
due
to
the
common
cold
in
combination
with
a
decongestant
(pseudoephedrine).
RECOMMENDED DOSAGE
_CHILD 6-11 YEARS:_ 2mg every 4 – 6 hours.
Maximum daily dose: 12mg per day.
_CHILD 12-17YEARS:_ 4mg every 4-6 hours.
Maximum daily dose: 24mg per day.
_ADULT:_ 4mg every 4-6 hours.
Maximum daily dose: 24mg per day.
_ELDERLY:_ 4mg every 4 – 6 hours.
Maximum daily dose: 12mg per day.
CONTRAINDICATIONS
Alleryl
Tablet