Kraj: Nowa Zelandia
Język: angielski
Źródło: Medsafe (Medicines Safety Authority)
Lansoprazole 15mg (Lansoprazole (R,S racemic mixture));
Douglas Pharmaceuticals Limited
Lansoprazole 15 mg (Lansoprazole (R,S racemic mixture))
15 mg
Capsule
Active: Lansoprazole 15mg (Lansoprazole (R,S racemic mixture)) Excipient: Gelatin Hypromellose Macrogol 6000 Mannitol Meglumine Methacrylic acid - ethyl acrylate copolymer Polysorbate 80 Purified talc Purified water Quinoline yellow Sodium laurilsulfate Sugar spheres Titanium dioxide
Blister pack, Al/Al non peelable, 28 capsules
Prescription
Prescription
Zhejiang Gold Pharma Co Ltd
Healing and long-term management of reflux oesophagitis Healing and maintenance therapy for patients with duodenal ulcer Healing of benign gastric ulcer Lansoprazole is also effective in patients with benign peptic lesions that do not respond to H2-receptor antagonists
Package - Contents - Shelf Life: Blister pack, Al/Al non peelable - 28 capsules - 36 months from date of manufacture stored at or below 25°C - Blister pack, Aluminium/aluminium peelable - 28 capsules - 36 months unopened stored at or below 25°C - Blister pack, Al/Al non peelable - 35 capsules - 36 months from date of manufacture stored at or below 25°C
2005-03-09
Medsafe Logo INFORMATION FOR CONSUMERS Home | Consumers | Health Professionals | Regulatory | Other | Hot Topics | Search Consumer Medicine Information SOLOX Lansoprazole 15 mg and 30 mg Capsules What is in this leaflet This leaflet answers some of the common questions about SOLOX. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighted the risks of you taking SOLOX with the benefits they expect it will have for you. If you have concerns about taking this medicine, ask your doctor or pharmacist. Keep this leaflet with your medicine. You may need to read it again. What SOLOX is used for The name of your medicine is SOLOX. It contains the active ingredient lansoprazole. SOLOX belongs to a group of medicines called proton pump inhibitors (PPI's). SOLOX works by decreasing the amount of acid the stomach produces, to give relief from symptoms and allow healing to occur. Ulcers SOLOX is used to treat or help heal peptic ulcers of the stomach and duodenum. These can be caused in part by too much acid being made in the stomach. SOLOX is also used to help stop duodenal ulcers coming back. Reflux Oesophagitis SOLOX is used to treat reflux oesophagitis or reflux disease. This is caused by "washing back" (reflux) of food and acid from the stomach into the oesophagus. Reflux can cause a burning sensation in the of food and acid from the stomach into the oesophagus. Reflux can cause a burning sensation in the chest rising up to the throat, also known as heartburn. Helicobacter pylori SOLOX can also be used in combination with certain antibiotics to help get rid of H. pylori infections in certain people with ulcers Przeczytaj cały dokument
SOLOX _LANSOPRAZOLE 15 MG AND 30 MG CAPSULES _ NAME OF THE MEDICINE SOLOX Lansoprazole 15 mg and 30 mg Capsules DESCRIPTION Lansoprazole is a substituted benzimidazole. It is a white to slightly brownish crystalline, acid-labile powder, slightly soluble in ethanol and almost insoluble in water (0.033 mg/mL), but more soluble at higher pH. It is a chiral compound with one centre (-SO) and is present as a racemic mixture. Lansoprazole melts at 165.8 ° C with decomposition and has a pKa of 8.8. Lansoprazole is chemically identified as 2[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulphinyl]-1H- benzimidazole. CAS number 103577-45-3, molecular weight is 369.36 and the molecular formula is C 16 H 14 F 3 N 3 0 2 S. The capsules contain as excipients: neutral pellets (made of corn and saccharose), sodium lauryl sulphate, N-Methylglucamine, mannitol, hydroxypropyl methylcellulose, polyethylene glycol 6000, talc, polysorbate 80, titanium dioxide, Eudragit ® (a methacrylic acid - ethyl acrylate copolymer). SOLOX 15 mg capsules contain gelatine, titanium dioxide and quinoline yellow in the capsule shell. SOLOX 30 mg capsules contain gelatine and titanium dioxide in the capsule shell. PHARMACOLOGY _MECHANISM OF ACTION _ Lansoprazole reduces gastric acid secretions by inhibiting the H + /K + -ATPase (proton pump) of the parietal cells in the gastric mucosa, the terminal phase of acid secretion. The drug is effective in the treatment of acid-related disorders of the upper gastrointestinal tract. A single dose of 30 mg lansoprazole inhibits stimulated acid secretion by approximately 80 %. Basal acid secretion and basal and stimulated secretion volumes are affected to a lesser degree. After repeated dosing (for 7 days) 90 % inhibition of stimulated acid secretion is achieved. Despite its short elimination half-life, lansoprazole has a prolonged pharmacological action, providing effective suppression of gastric acid secretion over 24 hours. When used in combination with the recommended antibiotics, SOLOX is associated Przeczytaj cały dokument