SALACYN salicylic acid cream

Kraj: Stany Zjednoczone

Język: angielski

Źródło: NLM (National Library of Medicine)

Składnik aktywny:

Salicylic Acid (UNII: O414PZ4LPZ) (Salicylic Acid - UNII:O414PZ4LPZ)

Dostępny od:

Stratus Pharamceuticals, Inc

INN (International Nazwa):

Salicylic Acid

Skład:

Salicylic Acid 24 g in 400 g

Typ recepty:

PRESCRIPTION DRUG

Status autoryzacji:

unapproved drug other

Charakterystyka produktu

SALACYN- SALICYLIC ACID CREAM
SALACYN- SALICYLIC ACID LOTION
STRATUS PHARAMCEUTICALS, INC
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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SALACYN™ 6% CREAM
SALACYN™ 6% LOTION
(6% Salicylic Acid)
RX ONLY
FOR DERMATOLOGICAL USE ONLY.
NOT FOR OPHTHALMIC, ORAL OR INTRAVAGINAL USE.
DESCRIPTION
SALACYN™ 6% CREAM contains 6% Salicyclic Acid USP incorporated into
a specially formulated
oil and water emulsion vehicle consisting of Ammonium Lactate,
Cetearyl Alcohol and PEG-3
Distearoylamidoethylmonium Methosulfate and Polysorbate 60, Cetearyl
Alcohol, Cetyl Alcohol,
Dimethicone 350, Disodium EDTA, Glycerin, Glyceryl Stearate SE,
Methylparaben, Mineral Oil, PEG-
100 Stearate, Phenoxyethanol, Propylparaben, Purified Water and
Trolamine.
SALACYN™ 6% LOTION contains 6% w/w Salicylic Acid USP incorporated
into a specially
formulated oil and water emulsion vehicle consisting of of Ammonium
Lactate, Cetearyl Alcohol and
PEG-3 Distearoylamidoethylmonium Methosulfate and Polysorbate 60,
Cetyl Alcohol, Dimethicone
350, Disodium EDTA, Glycerin, Glyceryl Stearate SE, Methylparben,
Mineral Oil, PEG-100 Stearate,
Propylparaben, Purified Water and Trolamine.
Salicylic Acid is the 2-hydroxy derivative of benzoic acid having the
following structure:
CLINICAL PHARMACOLOGY
Salicylic Acid has been shown to produce desquamation of the horny
layer of the skin while not
effecting qualitative or quantitative changes in the structure of the
viable epidermis. The mechanism of
action has been attributed to a dissolution of intercellular cement
substance. In a study of the
percutaneous absorption of salicylic acid in a 6% salicylic acid gel
in four patients with extensive
active psoriasis. Taylor and Halprin showed that the peak serum
salicylate levels never exceeded 5
mg/100 ml even though more than 60% of the applied salicylic acid was
absorbed. Systemic toxic
reactions are usually associated