Kraj: Australia
Język: angielski
Źródło: Department of Health (Therapeutic Goods Administration)
ascorbic acid,Biotin,calcium pantothenate,choline bitartrate,d-alpha-tocopherol,folic acid,inositol,magnesium sulfate trihydrate,nicotinamide,pyridoxine hydrochloride,riboflavine,thiamine nitrate,zinc sulfate monohydrate
Catalent Australia Pty Ltd
Ascorbic acid,Biotin,Calcium pantothenate,Choline bitartrate,d-alpha-Tocopherol,Folic acid,Inositol,magnesium sulfate trihydrate
Listed (Export Only)
MODURETIC ® 1 MODURETIC ® _amiloride hydrochloride dihydrate 5 mg/hydrochlorothiazide 50 mg _ CONSUMER MEDICINE INFORMATION (CMI) WHAT IS IN THIS LEAFLET This leaflet answers some common questions about MODURETIC. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking MODURETIC against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT MODURETIC IS USED FOR MODURETIC contains a combination of two diuretics, amiloride hydrochloride and hydrochlorothiazide as the active ingredients. MODURETIC is used to help reduce the amount of excess fluid in the body for people who have: • oedema, swelling of the ankles, feet and legs • ascites due to liver disease resulting in fluid accumulation in the stomach area. MODURETIC is also used to help people with hypertension or high blood pressure. Everyone has blood pressure. This pressure helps get your blood all around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension or high blood pressure when your blood pressure stays higher than is needed, even when you are calm and relaxed. There are usually no symptoms of hypertension. The only way of knowing that you have hypertension is to have your blood pressure checked on a regular basis. If high blood pressure is not treated it can lead to serious health problems. You may feel fine and have no symptoms, but eventually hypertension can cause stroke, heart disease and kidney failure. The combination of active ingredients in MODURETIC work by making your kidneys pass more water and salt whilst minimizing potassium loss. This helps reduce high blood pressure and some forms of swelling, while at the same time helping to maintain normal levels Przeczytaj cały dokument
MODURETIC – Full & Marketed Product Information Page 1 of 16 AUSTRALIAN PRODUCT INFORMATION MODURETIC (AMILORIDE HYDROCHLORIDE DIHYDRATE AND HYDROCHLOROTHIAZIDE) TABLETS 1.NAME OF THE MEDICINE Amiloride HCl dihydrate and hydrochlorothiazide 2 AND 3.QUALITATIVE AND QUANTITATIVE COMPOSITION AND PHARMACEUTICAL FORM Each MODURETIC tablet contains the following inactive ingredients: lactose monohydrate, calcium hydrogen phosphate dihydrate, maize starch, guar gum, pregelatinised maize starch, magnesium stearate and sunset yellow FCF lake CI15985. Excipients with known effect: Sugars as lactose MODURETIC tablets are plain, peach, diamond shaped, compressed tablets, containing hydrochlorothiazide 50 mg and amiloride HCl 5 mg. 4. CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS MODURETIC is indicated in the treatment of patients with - oedema of cardiac origin; - hepatic cirrhosis with ascites; - hypertension in whom potassium depletion might be anticipated. MODURETIC, with its combination of amiloride HCl and hydrochlorothiazide, minimises the possibility of the development of excessive potassium loss in patients during vigorous diuresis for prolonged periods. MODURETIC, with its built-in potassium sparing agent, is especially indicated in those conditions where the positive effect on potassium balance is particularly important. MODURETIC may be used alone, or as an adjunct to other antihypertensive drugs. Since it enhances the action of these agents, the dosage of these antihypertensive drugs may need to be reduced to avoid the risk of an excessive drop in blood pressure. 4.2 DOSE AND METHOD OF ADMINISTRATION Tablets MODURETIC are available for oral use containing 5 mg amiloride HCl and 50 mg hydrochlorothiazide. Oedema of Cardiac Origin MODURETIC – Full & Marketed Product Information Page 2 of 16 MODURETIC may be started at a dosage of 1 or 2 tablets a day. Dosage may be increased if necessary, but must not exceed four tablets a day. The optimal dosage is determined by the diuretic response and the serum potassium Przeczytaj cały dokument