PHENYLEPHRINE HYDROCHLORIDE INJECTION USP SOLUTION

Kraj: Kanada

Język: angielski

Źródło: Health Canada

Składnik aktywny:

PHENYLEPHRINE HYDROCHLORIDE

Dostępny od:

MARCAN PHARMACEUTICALS INC

Kod ATC:

C01CA06

INN (International Nazwa):

PHENYLEPHRINE

Dawkowanie:

10MG

Forma farmaceutyczna:

SOLUTION

Skład:

PHENYLEPHRINE HYDROCHLORIDE 10MG

Droga podania:

INTRAMUSCULAR

Sztuk w opakowaniu:

25X1ML

Typ recepty:

Ethical

Dziedzina terapeutyczna:

ALPHA-ADRENERGIC AGONISTS

Podsumowanie produktu:

Active ingredient group (AIG) number: 0100662004; AHFS:

Status autoryzacji:

APPROVED

Data autoryzacji:

2018-06-12

Charakterystyka produktu

PRESCRIBING INFORMATION
PHENYLEPHRINE HYDROCHLORIDE INJECTION USP
10 mg/mL
Marcan Pharmaceuticals Inc.,
Date of Preparation: 12 June, 2018
77 Auriga Drive, Suite#4,
Ottawa, ON, K2E 7Z7
Control # 209560
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PHENYLEPHRINE HYDROCHLORIDE INJECTION USP
10 mg/mL (1%)
THERAPEUTIC CLASSIFICATION
Vasopressor
PHARMACOLOGY
Phenylephrine Hydrochloride Injection USP is a vasoconstrictor and
pressor drug, chemically
related to epinephrine and ephedrine.
When applied topically or infiltrated into the tissues, phenylephrine
produces vasoconstriction that
lasts longer than that of epinephrine and ephedrine. Its action on the
heart contrasts sharply with
that of epinephrine and ephedrine, in that it slows the heart rate and
increases the stroke output,
inducing no disturbance in the rhythm of the pulse.
In therapeutic doses, it produces little if any stimulation of either
the spinal cord or cerebrum. A
singular advantage of this drug is the fact that repeated injections
produce comparable effects.
INDICATIONS AND CLINICAL USE
Phenylephrine Hydrochloride Injection USP is intended for the
maintenance of an adequate level of
blood pressure during spinal and inhalation anesthesia and for the
treatment of vascular failure in
shock, shock-like states, and drug-induced hypotension, or
hypersensitivity. It is also employed to
overcome paroxysmal supraventricular tachycardia, to prolong spinal
anesthesia, and as a
vasoconstrictor in regional analgesia.
PRECAUTIONS
Parenteral administration of Phenylephrine Hydrochloride Injection USP
may be contraindicated in
patients with hypertension or ventricular tachycardia, or in patients
who are hypersensitive to it, and
should be employed only with extreme caution in elderly patients or in
patients with
hyperthyroidism, bradycardia, partial heart block, myocardial disease,
or severe arteriosclerosis.
Vasopressors may cause serious cardiac arrhythmias during halothane
anesthesia and therefore
should be used only with great caution or not at all.
OXYTOCICS:
In obstetrics, if vasopressor drugs