MAROPITANT CITRATE tablet

Kraj: Stany Zjednoczone

Język: angielski

Źródło: NLM (National Library of Medicine)

Składnik aktywny:

MAROPITANT CITRATE (UNII: LXN6S3999X) (MAROPITANT - UNII:4XE2T9H4DH)

Dostępny od:

ZyVet Animal Health Inc

Droga podania:

ORAL

Typ recepty:

PRESCRIPTION

Wskazania:

Maropitant Citrate tablets are indicated for the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

Podsumowanie produktu:

Maropitant Citrate peach colored tablets are scored with a break line, and contain 16, 24, 60 or 160 mg of maropitant as maropitant citrate per tablet. Each tablet is marked with "31 and U","32 and U", "33 and U","34 and U" for 16, 24, 60 and 160mg respectively. Each tablet size is packaged in blister packs containing 4 tablets per perforated sheet.

Status autoryzacji:

Abbreviated New Animal Drug Application

Charakterystyka produktu

MAROPITANT CITRATE- MAROPITANT CITRATE TABLET
ZYVET ANIMAL HEALTH INC
----------
MAROPITANT CITRATE TABLETS
SPL UNCLASSIFIED
ANTIEMETIC
FOR ORAL USE IN DOGS ONLY
CAUTION
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION
Maropitant is a neurokinin (NK ) receptor antagonist that blocks the
pharmacological
action of substance P in the central nervous system (CNS). Maropitant
is the non-
proprietary designation for a substituted quinuclidine. The empirical
formula is
C
H
N O C H O H O and the molecular weight 678.81. The chemical name is
(2_S_,3_S_)-2-benzhydryl-_N-_(5_-tert_-butyl-2-methoxybenzyl)
quinuclidin-3-amine citrate
monohydrate. Each peach-colored oval tablet is scored and contains 16,
24, 60 or 160
mg of maropitant as maropitant citrate per tablet.
The chemical structure of maropitant citrate is:
INDICATIONS
Maropitant Citrate tablets are indicated for the prevention of acute
vomiting and the
prevention of vomiting due to motion sickness in dogs.
DOSAGE AND ADMINISTRATION
FOR PREVENTION OF ACUTE VOMITING
1
32
40
2
6
8
7
2
FOR PREVENTION OF ACUTE VOMITING IN DOGS 2 -7 MONTHS OF AGE:
Administer
Maropitant Citrate tablets orally at a minimum dose of 2 mg/kg (0.9
mg/lb) body weight
once daily for up to 5 consecutive days (see WARNINGS and Animal
Safety).
FOR PREVENTION OF ACUTE VOMITING IN DOGS 7 MONTHS OF AGE AND OLDER:
Administer Maropitant Citrate tablets orally at a minimum dose of 2
mg/kg (0.9 mg/lb)
body weight once daily until resolution of acute vomiting.
If vomiting persists despite treatment, the case should be
re-evaluated. Maropitant
Citrate is most effective in preventing acute vomiting associated with
chemotherapy if
administered prior to the chemotherapeutic agent.
FOR PREVENTION OF ACUTE VOMITING, DISPENSE WHOLE OR HALF TABLETS IN
STRENGTH(S) THAT MOST CLOSELY RESULT IN A 2 MG/KG DOSE:
DOG BODY WEIGHT
NUMBER OF TABLETS
POUNDS
KILOGRAMS
16 MG
24 MG
60 MG
8
4
½
15
8
1
25
12
1
50
24
2
65
30
1
130
60
2
INTERCHANGEABLE USE WITH MAROPITANT CITRATE INJE