ESCITALOPRAM GENERICHEALTH escitalopram (as oxalate) 15mg tablet blister pack

Kraj: Australia

Język: angielski

Źródło: Department of Health (Therapeutic Goods Administration)

Składnik aktywny:

escitalopram oxalate

Dostępny od:

Lupin Australia Pty Limited

INN (International Nazwa):

escitalopram oxalate

Status autoryzacji:

Registered

Ulotka dla pacjenta

Escitalopram generichealth CMI v2
Page 1 of 6
CONSUMER MEDICINE INFORMATION
ESCITALOPRAM-GENERICHEALTH
escitalopram oxalate
What is in this leaflet
This leaflet contains answers
to some common questions
about Escitalopram
generichealth. It does not
contain all the information
that is known about
Escitalopram generichealth. It
does not take the place of
talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has
weighed the risk of you using
this medicine against the
benefits he/she expects it will
have for you.
If you have any concerns
about using this medicine,
ask your doctor or
pharmacist.
Keep this leaflet with the
medicine. You may need to
read it again.
What Escitalopram
generichealth is used for
Escitalopram generichealth is
used to treat depression. It
belongs to a group of
medicines called selective
serotonin reuptake inhibitors
(SSRIs). They are thought to
work by their actions on brain
chemicals called amines
which are involved in
controlling mood.
Depression is longer lasting
or more severe than the "low
moods" everyone has from
time to time due to the stress
of everyday life. It is thought
to be caused by a chemical
imbalance in parts of the
brain. This imbalance affects
your whole body and can
cause emotional and physical
symptoms such as feeling
low in spirit, loss of interest in
activities, being unable to
enjoy life, poor appetite or
overeating, disturbed sleep,
often waking up early, loss of
sex drive, lack of energy and
feeling guilty over nothing.
Escitalopram generichealth
corrects this chemical
imbalance and may help
relieve the symptoms of
depression.
Escitalopram generichealth
may also be used to treat
patients who may avoid
and/or are fearful of social
situations.
Escitalopram generichealth
may also be used to treat
patients who have excessive
anxiety and worry.
Escitalopram generichealth
may also be used to treat
irrational fears or obsessional
behaviour (obsessive-
compulsive disorder).
Obsessive-compulsive
disorder involves having both
obsessions and co

Charakterystyka produktu

ESCITALOPRAM-GENERICHEALTH TABLETS
(LUPIN AUSTRALIA PTY. LTD)
NAME OF THE MEDICINE
Escitalopram-Generichealth Tablets 5 mg containing
escitalopram (as oxalate) 5 mg,
Escitalopram-Generichealth Tablets 10 mg containing
escitalopram (as oxalate) 10 mg,
Escitalopram-Generichealth Tablets 15 mg containing
escitalopram (as oxalate) 15 mg and
Escitalopram-Generichealth Tablets 20 mg containing
escitalopram (as oxalate) 20 mg
ESCITALOPRAM OXALATE
It
is
described
chemically
as
S
(+)-1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroiso
benzofuran-5-carbonitrile hydrogen oxalate. Escitalopram is the active
enantiomer (S-enantiomer)
of citalopram.
Molecular formula: C
20
H
21
FN
2
O, C
2
H
2
O
4
Molecular Weight: 414.42
CAS: 219861-08-2
Chemical structure:
DESCRIPTION
Escitalopram oxalate is a fine white to yellow, crystalline material.
Escitalopram oxalate is sparingly soluble in water, slightly soluble
in acetone, soluble in ethanol and
freely soluble in methanol. No polymorphic forms have been detected.
EXCIPIENTS
Microcrystalline
cellulose,
Croscarmellose
sodium,
,
Colloidal
silicon
dioxide,
Purified
talc,
Magnesium
stearate
and
Opadry White
Y-1-7000,
ARTG
no.
2731
(contains
Hypromellose,
Macrogol 400 and Titanium dioxide).
_Escitalopram-Generichealth tablet _
_Product Information _
_Lupin Australia Pty Ltd _
_V3 _
Page 2 of 33
PHARMACOLOGY
PHARMACODYNAMICS: Biochemical and behavioural studies have shown that
escitalopram is a
potent inhibitor of serotonin (5-HT)-uptake (_in vitro _IC
50
2nM).
The anti-depressant action of escitalopram is presumably linked to the
potentiation of serotonergic
activity in the central nervous system (CNS) resulting from its
inhibitory effect on the reuptake of 5-
HT from the synaptic cleft.
Escitalopram is a highly selective Serotonin Reuptake Inhibitor
(SSRI). On the basis of _ in vitro _
studies, escitalopram had no, or minimal effect on noradrenaline (NA),
dopamine (DA) and gamma
aminobutyric acid (GABA) uptake.
In contrast to many tricyclic anti-depressants and some of the SSRIs