COLIMIX SYRUP

Kraj: Singapur

Język: angielski

Źródło: HSA (Health Sciences Authority)

Składnik aktywny:

DICYCLOMINE HCl; SIMETHICONE

Dostępny od:

APEX PHARMA MARKETING PTE. LTD.

Kod ATC:

A03ED

Dawkowanie:

5 mg/5 ml

Forma farmaceutyczna:

SYRUP

Skład:

DICYCLOMINE HCl 5 mg/5 ml; SIMETHICONE 50 mg/5 ml

Droga podania:

ORAL

Typ recepty:

Pharmacy Only

Wyprodukowano przez:

XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD

Status autoryzacji:

ACTIVE

Data autoryzacji:

1989-06-16

Charakterystyka produktu

Important information. Please read carefully.
Colimix
®
Syrup
RELIEVES INFANT COLIC, WIND AND ABDOMINAL DISCOMFORT
COMPOSITION
Each 5 ml contains
Dicyclomine HCI
................................................................... 5
mg
Simethicone
........................................................................
50 mg
Parabens 0.25% w/v as preservative.
ACTIONS AND USES
Infant colic: Babies drink very quickly and they swallow much air with
their milk; especially when
bottle-fed. If the air is not expelled (e.g. by burping), the bubbles
get trapped in the digestive system.
Painful spasms (colic) develop as the intestines try to expel the
bubbles; and the baby cries without
stopping. COLIMIX breaks up the bubbles and relaxes the intestinal
muscles thus easing the pain
and helping baby to burp. In older children and adults, COLIMIX is
equally effective in relieving
flatulence (wind) and abdominal discomfort due to entrapped gas.
PHARMACODYNAMICS
Dicyclomine hydrochloride is a tertiary amine antimuscarinic with
effects similar to but weaker than
those of atropine. It also has a direct antispasmodic action.
Simeticone is a mixture of liquid dimeticones containing finely
divided silicon dioxide to enhance
the defoaming properties of the silicone. It lowers surface tension
and when given by mouth causes
bubbles of gas in the gastrointestinal tract to coalesce, thus aiding
their dispersion.
PHARMACOKINETICS
Dicyclomine is rapidly absorbed after oral dosing with peak plasma
concentrations occurring within
1 to 1.5 hours. Dicyclomine is excreted mainly in the urine (nearly
80% of a dose), with a small
amount in the faeces (about 8%). The mean elimination half-life for
the first 9 hours after a single
dose is about 1.8 hours.
DOSAGE
For oral administration only.
Unless otherwise prescribed by the physician:
Infants over 6 months : 5 ml before each feed. Do not exceed 4 doses
in 24 hours.
Children 4 to 12 years : 5 to 10 ml 4 times daily.
Adults : 10 ml 3 to 4 times daily and at bedtime.
Do not exceed the stated dose.