CIPROXIN ciprofloxacin 100mg/50mL injection

Kraj: Australia

Język: angielski

Źródło: Department of Health (Therapeutic Goods Administration)

Składnik aktywny:

ciprofloxacin

Dostępny od:

Bayer Australia Ltd

Status autoryzacji:

Registered

Ulotka dla pacjenta

191009 CIPROXIN IV CMI
1
CIPROXIN
® IV
(CI
⋅
PROX
⋅
IN)
_ciprofloxacin _
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS
LEAFLET
This leaflet answers some common
questions about Ciproxin IV. It does
not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you taking Ciproxin IV
against the benefits they expect it
will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE
MEDICINE.
You may need to read it again.
WHAT CIPROXIN IV IS
USED FOR
Ciproxin IV is used to treat serious
infections in the lungs, skin, blood,
bone, joints, kidneys, and bowel.
Ciproxin IV is also used to treat
inhalational anthrax (an infection
caused by breathing in the spores of
bacteria).
Ciproxin IV contains the active
ingredient, CIPROFLOXACIN
, which is
an antibiotic belonging to a group of
medicines called quinolones
(pronounced kwin-o-lones). These
antibiotics work by killing the
bacteria that are causing your
infection.
Ciproxin IV is used in hospitalised
patients where use of Ciproxin
tablets is inappropriate.
Ciproxin IV will not work against
infections caused by viruses such as
colds or the flu.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY THIS
MEDICINE HAS BEEN PRESCRIBED FOR
YOU.
Your doctor may have prescribed it
for another reason.
BEFORE YOU ARE
GIVEN CIPROXIN IV
_WHEN YOU MUST NOT BE _
_GIVEN IT _
YOU MUST NOT BE GIVEN CIPROXIN
IV IF YOU HAVE AN ALLERGY TO:
•
ciprofloxacin, the active
ingredient in Ciproxin IV
•
any of the ingredients listed at
the end of this leaflet
•
other medicines belonging to
the quinolone chemical family
(e.g. moxifloxacin, norfloxacin,
nalidixic acid)
Some of the symptoms of an
allergic reaction may include:
•
shortness of breath
•
wheezing or difficulty breathing
•
swelling of the face, lips,
tongue or other parts of the
body
•
rash, itching or hives on the skin
DO NOT USE CIPROX

Charakterystyka produktu

191009 CIPROXIN IV PI
Page 1 of 22
PRODUCT INFORMATION
CIPROXIN
® IV
Ciprofloxacin
NAME OF THE MEDICINE
Ciproxin
IV (ciprofloxacin) is a synthetic carboxyquinolone derivative with
broad spectrum
antimicrobial activity for intravenous (IV) administration.
Ciprofloxacin, a fluoroquinolone, is a
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline-carboxylic
acid. The
CAS Registry number is 85721-33-1. It is a faint to light yellow
crystalline powder with a
molecular weight of 331.4. Its empirical formula is C
17
H
18
FN
3
O
3
and its chemical structure
is as follows:
DESCRIPTION
Ciproxin IV (ciprofloxacin lactate) is available as a 100 mg/50 mL and
a 200 mg/100 mL
ready-to-use infusion solution in 0.9% sodium chloride injection.
Ciproxin IV also contains the
excipients: lactic acid, which is used as a solubilising agent,
hydrochloric acid for pH
adjustment, and water for injections. The solution is a clear,
colourless to slightly yellow
solution.
PHARMACOLOGY
PHARMACOLOGICAL ACTIONS (MICROBIOLOGY)
Ciprofloxacin has _in vitro_ and _in vivo_ activity against a wide
range of Gram-negative and
Gram-positive organisms. The bactericidal action of ciprofloxacin
appears to result from
interference with the enzyme, DNA gyrase.
Gram-negative organisms
_Escherichia_ _coli_; _Klebsiella_ species (including _Klebsiella_
_pneumoniae_ and _Klebsiella oxytoca_);
_Enterobacter _species; _Citrobacter_ species; _Salmonella_ species;
_Shigella_ species; _Proteus _
_mirabilis_; _Proteus vulgaris_; _Providencia stuartii_; _Providencia
rettgeri _(formerly _Proteus _
_rettgeri_); _Morganella_ _morganii_ (formerly _Proteus_ _morganii_);
_Serratia_ species (including
_Serratia marcescens_); _Pseudomonas aeruginosa_; _Pseudomonas
fluorescens_; _Haemophilus _
_influenzae_; _Moraxella _(_Branhamella_)_ catarrhalis_;
_Campylobacter _species.
Gram-positive organisms*
_Staphylococcus aureus_ (including methicillin susceptible and
methicillin-resistant strains);
coagulase negative _Staphylococcus_ species (including _Staphylococ