Cilicaine Syringe 1.5 1.5g injection

Kraj: Australia

Język: angielski

Źródło: Department of Health (Therapeutic Goods Administration)

Składnik aktywny:

procaine benzylpenicillin (procaine penicillin)

Dostępny od:

Mylan Health Pty Ltd

Klasa:

Medicine Registered

Status autoryzacji:

Registered

Ulotka dla pacjenta

CILICAINE Syringe- Consumer Medicine Information
Page 1 of 3
CILICAINE SYRINGE
_procaine penicillin _
CONSUMER MEDICINE INFORMATION (CMI)
W
W
H
H
A
A
T
T
I
I
S
S
I
I
N
N
T
T
H
H
I
I
S
S
L
L
E
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A
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F
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This leaflet answers some common
questions about CILICAINE. It does
not contain all the available
information. It does not take place of
talking to your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of using CILICAINE
against the benefits this medicine is
expected to have for you.
IF YOU HAVE ANY CONCERNS ABOUT
THIS MEDICINE, ASK YOUR DOCTOR OR
PHARMACIST.
KEEP THIS LEAFLET WITH YOUR
MEDICINE.
You may need to read it again.
WHAT IS CILICAINE USED
FOR
The name of your medicine is
CILICAINE syringe injection.
CILICAINE is a type of antibiotic
and belongs to the group of
medicines called penicillins. It
contains a penicillin, as an active
ingredient, which is called _Procaine _
_Penicillin._
CILICAINE syringe injection is
available as a 1.5 gram disposable
syringe with sterile swabs.
CILICAINE is used to treat
infections in different parts of the
body caused by bacteria. It works by
killing the bacteria that are causing
the infection. It will not work against
infections caused by viruses such as
colds or the flu.
Your doctor may have prescribed
this medicine for another purpose.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY CILICAINE
HAS BEEN PRESCRIBED FOR YOU.
CILICAINE is only available with a
doctor’s prescription.
BEFORE USING IT
_WHEN YOU MUST NOT BE GIVEN IT _
DO NOT USE CILICAINE IF YOU
HAVE EVER HAD AN ALLERGIC REACTION
TO:

CILICAINE syringe injection
or any other penicillin.

Any of the other ingredients in
CILICAINE listed at the end of
this leaflet.
YOU MUST TELL YOUR DOCTOR IF YOU
HAVE HAD AN ALLERGIC REACTION TO
CEPHALOSPORINS.
You may have an increased chance
of being allergic to CILICAINE if
you are allergic to cephalosporins.
Some of the symptoms of an allergic
reaction may include skin rash and
itching. Other reactions may in

Charakterystyka produktu

CILICAINE INJECTION- Product Information
Page 1 of 5
PRODUCT INFORMATION
CILICAINE SYRINGE 1.5 INJECTION
NAME OF DRUG
CILICAINE SYRINGE 1.5 INJECTION contains 1.5 g of _procaine
penicillin_.
The structural formula of procaine penicillin _(CAS 6130-64-9)_ is:
Its
chemical
name
is
2-diethylaminoethyl
4-aminobenzoate
(6R)-(2-phenylacetamido)
penicillinate monohydrate with an empirical formula of C
13
H
20
N
2
O
2
,C
16
H
18
N
2
O
4
S,H
2
O and a
molecular weight of 588.7.
_Physical and Chemical Properties_:
Procaine penicillin is a white crystalline powder. It is slightly
soluble in water (1 in 250 or
4.0 - 4.5 mg/mL), soluble in 96% alcohol (1 in 30 or 3.33 mg/mL) and
chloroform (1 in 60),
slightly soluble in acetone and fixed oils. A 0.33% aqueous suspension
has a pH of 5.0 to 7.5.
DESCRIPTION
Cilicaine Syringe 1.5 injection contains 1.5 g of procaine penicillin
in 3.4 mL. It is a sterile
buffered aqueous suspension.
Note: 1 unit = 1 microgram of pure procaine penicillin.
Cilicaine Syringe 1.5 injection is a slightly viscous white suspension
that has a faint odour
characteristic of penicillin.
_Excipients_: Phenyl mercuric acetate (used as a preservative), sodium
citrate, polysorbate 80
and water for injections.
PHARMACOLOGY
Benzylpenicillin
is
a
bactericidal
antibiotic
producing
its
effect
on
penicillin
sensitive
microorganisms during the stage of active multiplication through
inhibition of biosynthesis of
cell
wall
mucopeptides.
The
procaine
salt
has
low
solubility
and
is
administered
intramuscularly as a suspension of crystalline procaine penicillin.
These particles dissolve
slowly after administration, so that absorption from the injection
site takes place over a
CILICAINE INJECTION- Product Information
Page 2 of 5
prolonged period. Because absorption continues for up to 24 hours,
injection may be given
only once or twice daily or as initial treatment. A peak serum level
is reached in about 2
hours.
About 60% of benzylpenicillin is bound to serum proteins. The drug is
distributed throughout
the body tissues in