CERENIA- maropitant citrate injection

Kraj: Stany Zjednoczone

Język: angielski

Źródło: NLM (National Library of Medicine)

Składnik aktywny:

MAROPITANT CITRATE (UNII: LXN6S3999X) (MAROPITANT - UNII:4XE2T9H4DH)

Dostępny od:

Zoetis Inc.

INN (International Nazwa):

MAROPITANT CITRATE

Skład:

MAROPITANT 10 mg in 1 mL

Droga podania:

INTRAVENOUS

Typ recepty:

PRESCRIPTION

Wskazania:

Dogs: CERENIA (maropitant citrate) Injectable Solution is indicated for the prevention and treatment of acute vomiting in dogs. Cats : CERENIA (maropitant citrate) Injectable Solution is indicated for the treatment of vomiting in cats.

Podsumowanie produktu:

CERENIA Injectable Solution is supplied in 20 mL amber glass vials. Each mL contains 10 mg of maropitant as maropitant citrate.

Status autoryzacji:

New Animal Drug Application

Charakterystyka produktu

CERENIA- MAROPITANT CITRATE INJECTION
ZOETIS INC.
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CERENIA
(MAROPITANT CITRATE)
INJECTABLE SOLUTION
ANTIEMETIC
_For subcutaneous injection in dogs and cats_
CAUTION
Federal (USA) law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION
Maropitant is a neurokinin (NK1) receptor antagonist that blocks the
pharmacological
action of substance P in the central nervous system (CNS). Maropitant
is the non-
proprietary designation for a substituted quinuclidine. The empirical
formula is
C32H40N2O C6H8O7 H2O and the molecular weight 678.81. The chemical
name is
(2_S_,3_S)_-2-benzhydryl-_N_-(5-_tert_-butyl-2- methoxybenzyl)
quinuclidin-3-amine citrate
monohydrate. Each mL of CERENIA Injectable Solution contains 10 mg
maropitant, 63
mg sulphobutylether-beta-cyclodextrin, 3.3 mg meta-cresol and water
for injection.
The chemical structure of maropitant citrate is:
®
INDICATIONS
DOGS: CERENIA (maropitant citrate) Injectable Solution is indicated
for the prevention
and treatment of acute vomiting in dogs.
CATS: CERENIA (maropitant citrate) Injectable Solution is indicated
for the treatment of
vomiting in cats.
DOSAGE AND ADMINISTRATION
Use of refrigerated product may reduce the pain response associated
with
subcutaneous injection.
DOGS
FOR PREVENTION AND TREATMENT OF ACUTE VOMITING IN DOGS:
DOGS 2-4 MONTHS OF AGE: Administer CERENIA Injectable Solution
subcutaneously at
1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight
once daily for up
to 5 consecutive days.
DOGS 4 MONTHS OF AGE AND OLDER: Administer CERENIA Injectable Solution
intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45
mg/lb) equal to 0.1
mL/1 kg (1 mL/22 lb) of body weight once daily for up to 5 consecutive
days.
In dogs that are actively vomiting, it is recommended to initiate
treatment with CERENIA
Injectable Solution. Thereafter, CERENIA Tablets may be used for the
prevention of acute
vomiting at 2 mg/kg once daily. (See CERENIA Tablets package insert
for complete
prescribing informati