Kraj: Stany Zjednoczone
Język: angielski
Źródło: NLM (National Library of Medicine)
ACETAMINOPHEN (UNII: 362O9ITL9D) (ACETAMINOPHEN - UNII:362O9ITL9D)
7T Pharma LLC
ORAL
PRESCRIPTION DRUG
7T Gummy ES is used for the temporarily relief of minor aches and pain due to the common cold, flu, headache, sore throat, toothache, and temporarily reduces fever.
7T Gummy ES is supplied in the following dosage form: Eight (8) chewable gels per container Made in USA Rx Only Manufactured for: 7T Pharma, LLC 220 Emerald Vista Way Las Vegas, NV 89144 800.941.2848 NDC: 70645-500-88 Size: 8 Chewable Gels
unapproved drug other
7T GUMMY ES- ACETAMINOPHEN TABLET, CHEWABLE 7T PHARMA LLC _Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been_ _approved by FDA. For further information about unapproved drugs, click here._ ---------- 7T GUMMY ES 7T GUMMY ES (ACETAMINOPHEN CHEWABLE GELS 500 MG) 7T PHARMA, LLC ---------------- DESCRIPTION 7T Gummy ES is available as a chewable gel or gummy oral dosage form with improved organoleptic properties of taste, softness, chewiness, hardness, and translucency. Acetaminophen, 4’-hydroxyacetanilide, a slightly bitter, white, odorless, crystalline powder, is a non- opiate, non-salicylate analgesic and antipyretic. It has the following structural formula: In addition, each chewable gel contains the following inactive ingredients: hydroxypropyl betadex, seaweed extract (carrageenan), maltitol solution, sugar, sodium citrate, sodium chloride, sucralose, neotame, maltodextrin, glucose syrup, flavor, purified water. CLINICAL PHARMACOLOGY MECHANISM OR ACTION The precise mechanism of the analgesic properties of acetaminophen is not established but is thought to involve central nervous system actions. PHARMACODYNAMICS Therapeutic doses of acetaminophen have negligible effects on the cardiovascular or respiratory systems; however, toxic doses may cause circulatory failure and rapid, shallow breathing. PHARMACOKINETICS Acetaminophen is rapidly absorbed from the gastrointestinal tract and is distributed throughout most body tissues. A small fraction (10 to 25%) of acetaminophen is bound to plasma proteins. The plasma half-life is 1.25 to 3 hours, but may be increased by liver damage and following overdosage. Elimination of acetaminophen is principally by liver metabolism (conjugation) and subsequent renal excretion of metabolites. Acetaminophen is primarily metabolized in the liver by first-order kinetics and involves three principal separate pathways: conjugation with glucuronide; conjugation with sulfate; and oxidation via the cytochrome, P450-dependent, mixed-fu Przeczytaj cały dokument