FOBAN OINTMENT 2% ww

Land: Singapore

Språk: engelsk

Kilde: HSA (Health Sciences Authority)

Aktiv ingrediens:

SODIUM FUSIDATE

Tilgjengelig fra:

ZUELLIG PHARMA PTE. LTD.

ATC-kode:

D06AX01

Dosering :

2% w/w

Legemiddelform:

OINTMENT

Sammensetning:

SODIUM FUSIDATE 2% w/w

Administreringsrute:

TOPICAL

Resept typen:

Prescription Only

Produsert av:

HOE PHARMACEUTICALS SDN BHD

Autorisasjon status:

ACTIVE

Autorisasjon dato:

2002-02-20

Preparatomtale

Est. 1979
FOBAN CREAM AND OINTMENT
NAME AND STRENGTH OF ACTIVE SUBSTANCES :
CREAM: Fusidic Acid 2% w/w.
OINTMENT: Sodium Fusidate 2% w/w.
PRODUCT DESCRIPTION :
CREAM: A white cream.
Other ingredients: Propyl Paraben, Methyl Paraben, White Soft
Paraffin, Cetostearyl Alcohol,
Cetomacrogol 1000 (Macrogol Cetostearyl Ether), Propylene Glycol,
Liquid Paraffin and Purified
Water.
OINTMENT: A colourless ointment.
Other ingredients: Liquid Paraffin and White Soft Paraffin.
PHARMACODYNAMICS : Fusidic acid and its salts exert antibacterial
activity against most
Gram positive organisms; in particular, they are effective against
pathogenic Staphylococci,
including the penicillinase-producing strains. They have slight or no
activity against Gram
negative organisms and fungi.
PHARMACOKINETICS : Fusidic acid and its salts are widely distributed
into tissues and body
fluids, including bone, pus, and synovial fluid; they penetrate
cerebral abscesses but do not enter
cerebrospinal fluid in appreciable amounts. They have been found in
foetal circulation and in
breast milk. About 95% or more of Fusidic acid or Sodium fusidate in
the circulation is bound to
plasma protein. Fusidic acid or Sodium fusidate is excreted in the
bile, almost entirely as
metabolites, some of which have weak antimicrobial activity.
About 2% appears unchanged in the faeces. Little is excreted in the
urine or removed by
haemodialysis.
INDICATIONS
:
Skin
lesions
primarily
or
secondarily
infected
with
_Staphylococcus_
or
_Streptococcus._
CONTRAINDICATIONS : Known hypersensitivity to Fusidic acid, it salts
and propylene glycol.
DRUG INTERACTIONS : No synergy has been demonstrated in vitro in most
studies between
Fusidic acid and rifampicin or vancomycin, and antagonism of the
effects of ciprofloxacin has
been reported. Interactions with the penicillins are complex, with
either antagonism of the effect
of one or both agents, or lack of any efffect. However, the
combination of an antistaphylococcal
penicillin with Fusidic acid may prevent the emergence of Fusidic
a